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RNA turnover in eukaryotes : Analysis of specialized and quality control RNA decay pathways /

Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Maquat, Lynne (Editor ), Kiledjian, Megerditch (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego, California : Academic Press/Elsevier, �2008.
Colección:Methods in enzymology ; volume 449.
Temas:
Acceso en línea:Texto completo
Texto completo
Texto completo
Descripción
Sumario:Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. * Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway * Expert researchers introduce the most advanced technologies and techniques * Offers step-by-step lab instructions, including necessary equipment and reagents.
Descripción Física:1 online resource (xliv, 417 pages, 1 unnumbered leaf of plates) : illustrations (some color)
Bibliografía:Includes bibliographical references and indexes.
ISBN:9780080923321
0080923321
0123745845
9780123745842
ISSN:0076-6879 ;