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Advances in immunology. Vol. 98 /
Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecul...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Academic,
2008.
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| Edición: | 1. ed. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Cover; Copyright page; TOCContents; Contributors; CHChapter 1: Immune Regulation by B Cells and Antibodies: A View Towards the Clinic; Introduction; Prevention of Rhesus D Hemolytic Disease of the Newborn with Anti-D Antibodies; Antibody-Based Treatment of Immune Thrombocytopenia Purpura; Immune Regulating Functions of Na�ive and Activated B Cells; Acknowledgments; References; CHChapter 2: Cumulative Environmental Changes, Skewed Antigen Exposure, and the Increase of Allergy; Introduction; Antigen Exposure during Times When the Immune System Evolved
- Did Allergy Play a Role in the Evolution of the Human Immune System?Environmental and Lifestyle Changes Alter Humans' Antigen Exposure; Significant Changes in Lifestyle and Environment since H. sapiens Stated to Use Fire; Significant Lifestyle and Environmental Changes since the Industrial Revolution; The Increase in Proportions of Environmental Antigens of Limited Varieties; Prevalence of Allergy is Related to Changes in Antigen Exposure; The Hygiene Hypothesis and Its Immunological Basis; Key Factors Affecting the IgE-Mediated Pathway in Allergic Responses
- Total IgE vs. Allergen-Specific IgEAllergenic Substances Become Dominant Mucosal IgE Stimulators; Molecular Mechanisms Delineating the Effects of the Skewed Antigen Exposure on the Sensitization of the IgE Pathway; Concluding Remarks; Acknowledgments; References; CHChapter 3: New Insights on Mast Cell Activation via the High Affinity Receptor for IgE1; Introduction; A General Outline of FcepsivRI Signaling; Recent Advances in FcepsivRI Proximal Signaling; Regulation of Calcium Mobilization in Mast Cells; Sphingosine-1-phosphate: A Co-stimulatory Signal in FcepsivRI-mediated Mast Cell Ac
- The Role of Genetics in Mast Cell ResponsivenessSummary and Perspectives; References; CHChapter 4: B Cells and Autoantibodies in the Pathogenesis of Multiple Sclerosis and Related Inflammatory Demyelinating Diseases; MS and Related Inflammatory Demyelinating CNS Diseases; Therapeutic Depletion of B Cells in MS with Rituximab; Which B Cell Functions are Critical in the Pathogenesis of MS?; Conclusions and Future Directions; References; CHChapter 5: Human B Cell Subsets; Introduction; Human B Cell Subsets: Current Separation Schemes; Transitions in Peripheral B cell Development
- Monoclonal Antibodies from Human B Cell Subsets: Insights into Autoreactivity and FunctionVaccine-Induced Plasma Cells and Recombinant Antibodies: A Rapid Source of Fully Human Mabs; Autoimmune Disease and Human B Cell Subsets; Summary; References; IDXSubject Index; Contents of Recent Volumes