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Angiogenesis : in vivo systems /

Understanding how angiogenesis "works" and how to control it will have massive implications on the management, treatments, and ultimately the prevention of many common (and not so common) diseases. Angiogenesis is the growth of new blood vessels and is an important natural process in the b...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Cheresh, David A.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic, 2008.
Colección:Methods in enzymology ; v. 444.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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245 0 0 |a Angiogenesis :  |b in vivo systems /  |c editor, David A. Cheresh. Part B. 
260 |a London :  |b Academic,  |c 2008. 
300 |a 1 online resource (368 pages) 
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490 1 |a Methods in enzymology ;  |v v. 444 
588 0 |a Print version record. 
520 |a Understanding how angiogenesis "works" and how to control it will have massive implications on the management, treatments, and ultimately the prevention of many common (and not so common) diseases. Angiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance of angiogenesis modulators. In many serious disease states, however, the body loses control over angiogenesis. Diseases that are angiogenesis-dependent result when blood vessels either grow excessively or insufficiently. * Tried-and-tested techniques written by researchers that developed them, used them, and brought them to fruition * Provides the "builder's manual" for essential techniques--a one-stop shop that eliminates needless searching among untested techniques * Includes step-by-step methods for understanding the cell and molecular basis of wound healing, vascular integrin signaling, mechanical signaling in blood vessels, and vascular proteomics. 
505 0 |a Front Cover; Methods in Enzymology; Copyright Page; Contents; Contributors; Preface; Volumes in Series; Chapter 1: Molecular Mechanism of Type IV Collagen-Derived Endogenous Inhibitors of Angiogenesis; 1. Introduction; 3. Assessing the Role of Type IV Collagen-Derived Endogenous Inhibitor During Angiogenesis; References; Chapter 2: Chick Embryo Chorioallantoic Membrane Models to Quantify Angiogenesis Induced by Inflammatory and Tumor Cells or Purified Effector Molecules; 1. Introduction; 2. Overview of CAM Angiogenesis Models 
505 8 |a 3. Assessing the Role of Purified Effector Molecules and Cells in Angiogenesis Using CAM Collagen Onplant Model4. CAM Collagen Onplant Assay Protocol; 5. Validation of CAM Angiogenesis Findings in Collagen Implant Mouse Model; Acknowledgment; References; Chapter 3: The Adenoviral Vector Angiogenesis/Lymphangiogenesis Assay; 1. Introduction; 3. Blood Vessels Induced by Ad-VEGF-A164; Chapter 4: Using the Zebrafish to Study Vessel Formation; 1. Introduction; 4. Conclusion; Chapter 5: Evaluating Vascular Leak in Vivo; 1. Introduction; 2. Mechanisms of Vascular Leak 
505 8 |a 3. Consequences of Vascular Leak in Disease4. Models to Study Vascular Leak In Vivo; 5. Concluding Remarks; Chapter 6: Ocular Models of Angiogenesis; 2. Techniques Commonly Used in Ocular Angiogenesis Protocols; 3. Corneal Micropocket Assay; 4. Neonatal Mouse Retinal Developmental Angiogenesis Model; 6. Laser-induced Retinal and Choroidal Neovascularization Models; 9. Cell-based Models and Ocular Angiogenesis; Chapter 7: Mouse Models of Ischemic Angiogenesis and Ischemia-Reperfusion Injury; 1. Introduction; 2. Overview of Methods in Hindlimb I/R Injury 
505 8 |a 4. Overview of Methods in Chronic Hindlimb Ischemia6. Conclusion; References; Chapter 8: Noninvasive Imaging of Blood Vessels; 1. Introduction; References; Chapter 9: Intravital Videomicroscopy in Angiogenesis Research; 1. Introduction; 3. Summary; Acknowledgments; Chapter 10: In Vivo Measurements of Blood Flow and Glial Cell Function with Two-Photon Laser-Scanning Microscopy; 1. Introduction; 3. Photoprocesses for Targeted Disruption of Vascular Flow; Acknowledgments; Chapter 11: The Role of Bone Marrow-Derived Cells in Tumor Angiogenesis and Metastatic Progression; 1. The Angiogenic Switch 
505 8 |a 3. Bone-Marrow-Derived Cells: Endothelial and Hematopoietic Progenitor Cells4. Bone Marrow-Cell Mobilization in Response to Tumor Factors; 9. Stromal Cells: Carcinoma-Associated Fibroblasts (CAFs); 11. Future Directions; References; Chapter 12: Structure of Microvascular Networks in Genetic Hypertension; 1. Introduction; 2. Methods; 3. Results; 4. Discussion; 5. Summary; References; Chapter 13: Oxygen as a Direct and Indirect Biological Determinant in the Vasculature; 1. Introduction; 3. Physiological, Pathophysiological, and Clinical Settings in Which Oxygen Levels Influence the Vasculature 
504 |a Includes bibliographical references and indexes. 
650 0 |a Neovascularization. 
650 2 |a Neovascularization, Pathologic  |0 (DNLM)D009389 
650 6 |a N�eovascularisation.  |0 (CaQQLa)201-0162856 
650 7 |a Neovascularization  |2 fast  |0 (OCoLC)fst01035916 
700 1 |a Cheresh, David A. 
776 |z 0-12-374313-3 
830 0 |a Methods in enzymology ;  |v v. 444. 
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