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Programmed cell death. Part B, The biology and therapeutic implications of cell death /
One of the major goals of researchers in the field of apoptosis is to identify targets for novel therapies in cancer, AIDS, and Alzheimer's disease. Understanding the molecular mechanisms of the various components of the apoptotic pathways is the first step to reaching this goal. The 2002 Nobel...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, California :
Academic Press/Elsevier,
�2008.
|
| Colección: | Methods in enzymology ;
v. 446. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo Texto completo |
MARC
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| 245 | 0 | 0 | |a Programmed cell death. |n Part B, |p The biology and therapeutic implications of cell death / |c edited by Roya Khosravi-Far, Zahra Zakeri, Richard A. Lockshin, Mauro Piacentini. |
| 246 | 3 | 0 | |a Biology and therapeutic implications of cell death |
| 260 | |a San Diego, California : |b Academic Press/Elsevier, |c �2008. | ||
| 300 | |a 1 online resource (xlviii, 450 pages, 6 unnumbered pages of plates) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
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| 490 | 1 | |a Methods in enzymology, |x 0076-6879 ; |v v. 446 | |
| 504 | |a Includes bibliographical references and indexes. | ||
| 588 | 0 | |a Print version record. | |
| 520 | |a One of the major goals of researchers in the field of apoptosis is to identify targets for novel therapies in cancer, AIDS, and Alzheimer's disease. Understanding the molecular mechanisms of the various components of the apoptotic pathways is the first step to reaching this goal. The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner (United Kingdom), H. Robert Horvitz (US) and John E. Sulston (UK) "for their discoveries concerning genetic regulation of organ development and programmed cell death." Cell death is a fundamental aspect of embryonic development, normal cellular turnover and maintenance of homeostasis (maintaining a stable, constant environment) on the one hand, and aging and disease on the other. This volume addresses the significant advances with the techniques that are being used to analyze cell death. * This volume provides the necessary, trusted methods to carry out this research on these latest therapeutic techniques. Once researchers understand the molecular mechanisms of the apoptotic pathways, they can begin to develop new therapies. * Presents key methods on studying tumors and how these cancer cells evade cell death. * Eliminates searching through many different sources to avoid pitfalls so the same mistakes are not made over and over. | ||
| 546 | |a English. | ||
| 505 | 0 | |6 880-01 |a Analysis of autographic and necrotic cell death in Dictyostelium / C. Giusti... [at al.]. -- Methods and protocols for studying cell death in Drosophila / D. Denton, K. Mills, S. Kumar. -- In Vivo and In Vitro methods for studying apoptotic cell engulfment in Drosophia / E.A. Silva, J. Burden, N.C. Franc. -- A mouse mammary epithelial cell model to identify molecular mechanisms regulating breast cancer progression / V. Karantza-Wadsworth, E. White. -- Immortalized mouse epithelial cell models to study the role of apoptosis in cancer / R. Matthew... [et al.]. -- DNA damage response and apoptosis / D. Plesca, S. Muzumder, A. Almason. -- Phorbol ester-induced apoptosis and senescene in cancel cell models / L. Xiao... [et al.]. -- Manipulation of PKC isozymes by RNA interference and inducible expression of OKC constructs / A. Basu, S.D. Persaud, U. Sivaprasad. -- Studying p53-dependent cell death In Vitro and In Vivo / K. Kuribayashi, N. Finnberg, W.S. El-Deiry. -- NF-kB as a determinant of distinct dell death pathways / I.L. Ch�en, S.M. Hedrick, A. Hoffmann. -- Purification and bioassay of hedgehog ligans for the study of cell dealth and survival / P. Martinez-Chinchilla, N.A. Riobo. -- Experimental approaches to investiage the proteasomal degradation pathways involved in regulaiton of apoptosis / A. Tseng... [et al.]. -- Ubiquitination mediated by inhibitor of apoptosis proteins / Sun-Mi. Park... [et al.]. -- Phosphatases and regulation of cell death / Chi-Wu Chiang, L. Yan, E. Yang. -- Analysis of neuronal cell death in mammals / M. D'Amelio... [et al.]. -- Diissecting apoptosis and intrinsic death pathways in the heart / D. Weidman...[et al.]. -- Quantification of vascular endothelial cell apoptosis In Vivo / X. Zhang, S. Parangi. -- Recombinant TRAIL and TRAIL receptor analysis / N. Harper, M. MacFarlane. -- Analysis of Tnf-related apoptosis-inducing ligand In Vivo through bone marrow transduction and transplantation / K. Song, R. Mariappan, R. Khosravi-Far. -- Overcoming resistance to TRAIL-induced apoptosis in prostate cancer by regulation of c-Flip / X. Zhang, W. Li. A.F. Olumi. -- Caspase assays: identifying caspase activity and substrates In Vitro and In Vivo / C. Pop, G.S. Salvesen, F.L. Scott. -- Synthesis and biophysical characterization of staiblized ₍-Helices of BCL-2 domains / G. H. Bird... [et al.]. -- Dissection of the BCL-2 family signaling network with stabilized ₍-Helices of BCL-2 domains / K. Pitter... [et al.]. -- ERM-mediated genetic screens in mammalian cells / D. Liu, Z. Songyang | |
| 650 | 0 | |a Apoptosis. | |
| 650 | 0 | |a Cancer cells |x Variation. | |
| 650 | 1 | 2 | |a Cell Death |0 (DNLM)D016923 |
| 650 | 2 | 2 | |a Apoptosis |0 (DNLM)D017209 |
| 650 | 6 | |a Apoptose. |0 (CaQQLa)201-0222225 | |
| 650 | 6 | |a Cellules canc�ereuses |x Variation. |0 (CaQQLa)201-0200399 | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Anatomy & Physiology. |2 bisacsh | |
| 650 | 7 | |a Apoptosis |2 fast |0 (OCoLC)fst00811467 | |
| 650 | 7 | |a Cancer cells |x Variation |2 fast |0 (OCoLC)fst00845576 | |
| 653 | 0 | 0 | |a apoptose |
| 653 | 0 | 0 | |a apoptosis |
| 653 | 1 | 0 | |a Cellular Biology |
| 653 | 1 | 0 | |a Celbiologie |
| 655 | 2 | |a Congress |0 (DNLM)D016423 | |
| 655 | 7 | |a proceedings (reports) |2 aat |0 (CStmoGRI)aatgf300027316 | |
| 655 | 7 | |a Conference papers and proceedings |2 fast |0 (OCoLC)fst01423772 | |
| 655 | 7 | |a Conference papers and proceedings. |2 lcgft | |
| 655 | 7 | |a Actes de congr�es. |2 rvmgf |0 (CaQQLa)RVMGF-000001049 | |
| 700 | 1 | |a Khosravi-Far, Roya, |e editor. | |
| 700 | 1 | |a Zakeri, Zahra, |d 1952- |e editor. | |
| 700 | 1 | |a Lockshin, R. A. |q (Richard A.), |e editor. | |
| 700 | 1 | |a Piacentini, Mauro, |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Programmed cell death. Part B, The biology and therapeutic implications of cell death. |d San Diego, California : Academic Press/Elsevier, �2008 |z 0123744644 |w (OCoLC)244287019 |
| 830 | 0 | |a Methods in enzymology ; |v v. 446. |x 0076-6879 | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00766879/446 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780123744647 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00766879 |z Texto completo |
| 880 | 0 | |6 505-01/(S |a Analysis of autographic and necrotic cell death in Dictyostelium / C. Giusti ... [at al.].-- Methods and protocols for studying cell death in Drosophila / D. Denton, K. Mills, S. Kumar.-- In Vivo and In Vitro methods for studying apoptotic cell engulfment in Drosophia / E.A. Silva, J. Burden, N.C. Franc.-- A mouse mammary epithelial cell model to identify molecular mechanisms regulating breast cancer progression / V. Karantza-Wadsworth, E. White.-- Immortalized mouse epithelial cell models to study the role of apoptosis in cancer / R. Matthew [and others].-- DNA damage response and apoptosis / D. Plesca, S. Muzumder, A. Almason.-- Phorbol ester-induced apoptosis and senescene in cancel cell models / L. Xiao [and others].-- Manipulation of PKC isozymes by RNA interference and inducible expression of OKC constructs / A. Basu, S.D. Persaud, U. Sivaprasad.-- Studying p53-dependent cell death In Vitro and In Vivo / K. Kuribayashi, N. Finnberg, W.S. El-Deiry.-- NF-kB as a determinant of distinct dell death pathways / I.L. Ch�en, S.M. Hedrick, A. Hoffmann.-- Purification and bioassay of hedgehog ligans for the study of cell death and survival / P. Martinez-Chinchilla, N.A. Riobo.-- Experimental approaches to investigate the proteasomal degradation pathways involved in regulation of apoptosis / A. Tseng [and others].--Ubiquitination mediated by inhibitor of apoptosis proteins / Sun-Mi. Park [and others].-- Phosphatases and regulation of cell death / Chi-Wu Chiang, L. Yan, E. Yang.-- Analysis of neuronal cell death in mammals / M. D'Amelio [and others].-- Dissecting apoptosis and intrinsic death pathways in the heart / D. Weidman [and others].-- Quantification of vascular endothelial cell apoptosis In Vivo / X. Zhang, S. Parangi.-- Recombinant TRAIL and TRAIL receptor analysis / N. Harper, M. MacFarlane.-- Analysis of Tnf-related apoptosis-inducing ligand In Vivo through bone marrow transduction and transplantation / K. Song, R. Mariappan, R. Khosravi-Far.-- Overcoming resistance to TRAIL-induced apoptosis in prostate cancer by regulation of c-Flip / X. Zhang, W. Li, A.F. Olumi.-- Caspase assays: identifying caspase activity and substrates In Vitro and In Vivo / C. Pop, G.S. Salvesen, F.L. Scott.-- Synthesis and biophysical characterization of stabilized α-Helices of BCL-2 domains / G.H. Bird [and others].-- Dissection of the BCL-2 family signaling network with stabilized α-Helices of BCL-2 domains / K. Pitter [and others].-- ERM-mediated genetic screens in mammalian cells / D. Liu, Z. Songyang. | |