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Meiosis and gametogenesis /
In spite of the fact that the process of meiosis is fundamental to inheritance, surprisingly little is understood about how it actually occurs. There has recently been a flurry of research activity in this area and this volume summarizes the advances coming from this work. All authors are recognized...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
�1998.
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| Colección: | Current topics in developmental biology ;
v. 37. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Meiosis and Gametogenesis; Copyright Page; Contents; Contributors; Preface; Chapter 1. Recombination in the Mammalian Germ Line; I. Introduction; II. Problems Posed by the Mammalian System of Gametogenesis; III. Crossing Over; IV. Gene Conversion; V. Recombination and Disease; VI. Genetic Control of Recombination; VII. Conclusion; References; Chapter 2. Meiotic Recombination Hotspots: Shaping the Genome and Insights into Hypervariable Minisatellite DNA Change; I. Introduction; II. General Features of Chromosome Dynamics during Meiosis
- III. Genetic Identification of Recombination HotspotsIV. Double-Strand DNA Breaks and Open Chromatin; V. Roles of Protein-DNA Binding in Hotspot Activation; VI. Control of Recombination in cis and in trans, Near and Far; VII. Hotspots as Initiators or Resolvers of Recombination: Two Models; VIII. Summary; References; Chapter 3. Pairing Sites and the Role of Chromosome Pairing in Meiosis and Spermatogenesis in Male Drosophila; I. Introduction; II. Meiotic Pairing Sites in Chromosomes of Drosophila Males: Distribution, Molecular Composition, and Function
- III. Chromosome Pairing and SpermiogenesisIV. Summary and Implications; References; Chapter 4. Functions of DNA Repair Genes during Meiosis; I. DNA Repair and Organismal Physiology; II. Pathways of DSB Repair; III. Genetics of DSB Repair; IV. Relative Abundance of Homology-Based DSB Repair Events; V.A Coprinus cinereus Epistasis Group for DNA Repair and Meiosis; VI. Conclusions and Perspective; References; Chapter 5. Gene Expression during Mammalian Meiosis; I. Introduction; II. RNA Synthesis during Meiosis; III. Genes Expressed during Meiosis; IV. Conclusion; References
- Chapter 6. Caught in the Act: Deducing Meiotic Function from Protein ImmunolocalizationI. The Plot; II. Setting the Stage: Meiosis Plain and Simple; III. Surveillance Methods; IV. Reconstructing the Scene; V. Verifying an Alibi (Temporal and Spatial Resolution); VI. Developing a List of Suspects; VII. Setting Up a Sting Operation; VIII. Preliminary Conclusions; IX. Unsolved Cases; Chapter 7. Chromosome Cores and Chromatin at Meiotic Prophase; I. Introduction; II. SC Structure from Electron Microscopy; III. SC Structure from lmmunocytology
- IV. Chromatin Loop Attachments to the Meiotic Chromosome CoresV. Sequences Associated with the Core; VI. DNA Content of the Chromatin Loops; VII. Time Course of Chromatin Loop Development at Meiosis; VIII. Alignment of Chromatin Loops; IX. Recombination at the SC; References; Chapter 8. Chromosome Segregation during Meiosis: Building an Unambivalent Bivalent; I. Introduction; II. Mechanism of Chromosome Orientation; III. Chiasmata; IV. Homolog Attachment and Segregation without Chiasmata; V. Sister Kinetochore Function; VI. Maintaining Attachment between Sister Chromatids for Meiosis II