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Meiosis and gametogenesis /

In spite of the fact that the process of meiosis is fundamental to inheritance, surprisingly little is understood about how it actually occurs. There has recently been a flurry of research activity in this area and this volume summarizes the advances coming from this work. All authors are recognized...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Handel, Mary Ann
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press, �1998.
Colección:Current topics in developmental biology ; v. 37.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Meiosis and gametogenesis /  |c edited by Mary Ann Handel. 
260 |a San Diego :  |b Academic Press,  |c �1998. 
300 |a 1 online resource (xv, 422 pages) :  |b illustrations. 
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490 1 |a Current topics in developmental biology,  |x 0070-2153 ;  |v v. 37 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
520 |a In spite of the fact that the process of meiosis is fundamental to inheritance, surprisingly little is understood about how it actually occurs. There has recently been a flurry of research activity in this area and this volume summarizes the advances coming from this work. All authors are recognized and respected research scientists at the forefront of research in meiosis. Of particular interest is the emphasis in this volume on meiosis in the context of gametogenesis in higher eukaryotic organisms, backed up by chapters on meiotic mechanisms in other model organisms. The focus is on modern molecular and cytological techniques and how these have elucidated fundamental mechanisms of meiosis. Authors provide easy access to the literature for those who want to pursue topics in greater depth, but reviews are comprehensive so that this book may become a standard reference. Key Features * Comprehensive reviews that, taken together, provide up-to-date coverage of a rapidly moving field * Features new and unpublished information * Integrates research in diverse organisms to present an overview of common threads in mechanisms of meiosis * Includes thoughtful consideration of areas for future investigation. 
505 0 |a Front Cover; Meiosis and Gametogenesis; Copyright Page; Contents; Contributors; Preface; Chapter 1. Recombination in the Mammalian Germ Line; I. Introduction; II. Problems Posed by the Mammalian System of Gametogenesis; III. Crossing Over; IV. Gene Conversion; V. Recombination and Disease; VI. Genetic Control of Recombination; VII. Conclusion; References; Chapter 2. Meiotic Recombination Hotspots: Shaping the Genome and Insights into Hypervariable Minisatellite DNA Change; I. Introduction; II. General Features of Chromosome Dynamics during Meiosis 
505 8 |a III. Genetic Identification of Recombination HotspotsIV. Double-Strand DNA Breaks and Open Chromatin; V. Roles of Protein-DNA Binding in Hotspot Activation; VI. Control of Recombination in cis and in trans, Near and Far; VII. Hotspots as Initiators or Resolvers of Recombination: Two Models; VIII. Summary; References; Chapter 3. Pairing Sites and the Role of Chromosome Pairing in Meiosis and Spermatogenesis in Male Drosophila; I. Introduction; II. Meiotic Pairing Sites in Chromosomes of Drosophila Males: Distribution, Molecular Composition, and Function 
505 8 |a III. Chromosome Pairing and SpermiogenesisIV. Summary and Implications; References; Chapter 4. Functions of DNA Repair Genes during Meiosis; I. DNA Repair and Organismal Physiology; II. Pathways of DSB Repair; III. Genetics of DSB Repair; IV. Relative Abundance of Homology-Based DSB Repair Events; V.A Coprinus cinereus Epistasis Group for DNA Repair and Meiosis; VI. Conclusions and Perspective; References; Chapter 5. Gene Expression during Mammalian Meiosis; I. Introduction; II. RNA Synthesis during Meiosis; III. Genes Expressed during Meiosis; IV. Conclusion; References 
505 8 |a Chapter 6. Caught in the Act: Deducing Meiotic Function from Protein ImmunolocalizationI. The Plot; II. Setting the Stage: Meiosis Plain and Simple; III. Surveillance Methods; IV. Reconstructing the Scene; V. Verifying an Alibi (Temporal and Spatial Resolution); VI. Developing a List of Suspects; VII. Setting Up a Sting Operation; VIII. Preliminary Conclusions; IX. Unsolved Cases; Chapter 7. Chromosome Cores and Chromatin at Meiotic Prophase; I. Introduction; II. SC Structure from Electron Microscopy; III. SC Structure from lmmunocytology 
505 8 |a IV. Chromatin Loop Attachments to the Meiotic Chromosome CoresV. Sequences Associated with the Core; VI. DNA Content of the Chromatin Loops; VII. Time Course of Chromatin Loop Development at Meiosis; VIII. Alignment of Chromatin Loops; IX. Recombination at the SC; References; Chapter 8. Chromosome Segregation during Meiosis: Building an Unambivalent Bivalent; I. Introduction; II. Mechanism of Chromosome Orientation; III. Chiasmata; IV. Homolog Attachment and Segregation without Chiasmata; V. Sister Kinetochore Function; VI. Maintaining Attachment between Sister Chromatids for Meiosis II 
546 |a English. 
650 0 |a Meiosis. 
650 0 |a Gametogenesis. 
650 1 2 |a Meiosis  |x genetics  |0 (DNLM)D008540Q000235 
650 2 2 |a Gametogenesis  |x genetics  |0 (DNLM)D005718Q000235 
650 2 2 |a Germ Cells  |x cytology  |0 (DNLM)D005854Q000166 
650 2 |a Meiosis  |0 (DNLM)D008540 
650 2 |a Gametogenesis  |0 (DNLM)D005718 
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650 6 |a Gam�etogen�ese.  |0 (CaQQLa)201-0078714 
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650 7 |a Meiosis  |2 fast  |0 (OCoLC)fst01015610 
650 1 7 |a Meiose.  |2 gtt 
650 7 |a Genetica molecular e de microorganismos.  |2 larpcal 
700 1 |a Handel, Mary Ann. 
776 0 8 |i Print version:  |t Meiosis and gametogenesis.  |d San Diego : Academic Press, �1998  |z 9780121531379  |z 0121531376  |w (OCoLC)37933435 
830 0 |a Current topics in developmental biology ;  |v v. 37. 
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