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Advances in immunology. Volume 69 /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego ; London :
Academic Press,
�1998.
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| Colección: | Advances in immunology.
|
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Front Cover; Advences in Immunology, Volume 69; Copyright Page; Contents; Contributors; Chapter 1. Molecular and Cellular Events in Early Thymocyte Development; I. Introduction; II. Assays to Study Thymocyte Development in Vivo and in Vitro; III. Origin of Thymocytes: Hematopoietic Stem Cells and Early Thymocyte Progenitors; IV. Role of the Pre-T-Cell Receptor Complex in Thymocyte Development and Allelic Exclusion of the TCR � Chain; V. Growth/Differentiation Factors in Early Thymocyte Development; VI. Transcription Factors in Early Thymocyte Development.
- VII. Miscellaneous Mutations and Their Roles in Early Thymocyte DevelopmentReferences; Chapter 2. Regulation of Immunoglobulin Light Chain lsotype Expression; I. Antibody Molecules and Immunoglobulin Gene Assembly; II. Allelic Exclusion of Immunoglobulin Loci; III. Tissue- and Stage-Specific Control of Immunoglobulin Light K Expression; IV. Regulation of Immunoglobulin Light Chain Gene Rearrangement; References; Chapter 3. Role of lmmunoreceptor Tyrosine-Based Activation Motif in Signal Transduction from Antigen and Fc Receptors; I. Introduction.
- II. Structure and Function of Immunoreceptor Tyrosine-Based Activation Motifs (ITAMs)III. ITAMs Interaction with Protein Tyrosine Kinases (PTKs); IV. ITAMs as Scaffolds for Multiple Effector Molecules; V. Involvement of ITAMs in Tolerance Induction and Immunopathology; VI. Temporal and Spatial Determinants That Coordinate Downregulation of ITAM-Induced Activation Signals; VII. Perspectives and Concluding Remarks; References; Chapter 4. The Atypical Serine Proteases of the Complement System; I. Serine Proteases in the Complement System.
- II. The Serine Protease Domain: Shared Features and Unique Structural Elementsof Complement ProteasesIII. Modular Structure of Complement Proteases; IV. Structure and Function of Complement Proteases; V. Summary and Perspectives; References; Chapter 5. Accessibility Control of V(D)J Recombination: Lessons from Gene Targeting; I. Introduction; II. Basic Features; III. Role of cis-Acting Elements: Trial of the Homologous Recombination Approach; IV. Targeted Mutation of trans-Regulatory Factors; V. Biological Consequences; References.
- Chapter 6. Interactions between the Immune System and Gene Therapy Vectors: Bidirectional Regulation of Response and ExpressionI. Introduction; II. Immunity to Vectors; III. Immunity to Gene Transfer Products; IV. Cytokine Regulation of Promoter Function; V. Immunostimulatory DNA Sequences; VI. Alteration of Immune Function by Viral Products; VII. Transfer Vectors as Enhancers of Antigen Presentation; VIII. Conclusions; References; Chapter 7. How Do Major Histocompatibility Complex Genes Influence Individual Odor and Mating Preferences?; I. Introduction.