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Advances in immunology. Volume 63 /

Praise for the Series: "The series which all immunologists need."--The Pharmaceutical Journal "Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions."--Science "Deserves a permanent place in biomedical lib...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Dixon, Frank J. (Frank James), 1920-2008
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Academic Press, �1996.
Colección:Advances in immunology.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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245 0 0 |a Advances in immunology.  |n Volume 63 /  |c edited by Frank J. Dixon. 
260 |a New York :  |b Academic Press,  |c �1996. 
300 |a 1 online resource (x, 468 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
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490 1 |a Advances in Immunology ;  |v v. 63 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
520 |a Praise for the Series: "The series which all immunologists need."--The Pharmaceutical Journal "Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions."--Science "Deserves a permanent place in biomedical libraries as an aid in research and in teaching."--Journal of Immunological Methods Key Features: * The role of CD40 and its ligand, gp39, as central players in the regulation of B cell growth and differentiation * Prolactin, growth hormone and insulin-like growth factor-I as full-fledged immunological growth and differentiation factors * Transcription factors of functionally mutant mice are highly relevant to understanding hemopoiesis and B cell genesis in vivo HIV infection of xenotransplanted mice compared with natural HIV and SIV infections * The expression and role of cytokines in Rheumatoid Arthritis and in seronegative arthritis * The functions of the surrogate light chain in B cell development * Mechanisms that regulate cytokine activity and the generation and function of sCR as cytokine anatogonists and/or cytokine "carriers" in vivo * Potential transducing molecules involved in signaling processes and which mark the difference between signaling through IL-2R and IL-4R 
505 0 |a Front Cover; Advances in Immunology, Volume 63; Copyright Page; Contents; Contributors; Chapter 1. Surrogate Light Chain in B Cell Development; I. Introduction; II. Surrogate Light Chain Genes and Their Regulation; III. Expression of Surrogate Light Chain; IV. Functional Roles of Surrogate Light Chain in B Cell Development; V. Ligand and Signal Transduction of Surrogate Light Chain Complex; VI. Other Surrogate Light Chain-like Molecules; VII. Concluding Remarks; References; Chapter 2. CD40 and Its Ligand; I. Introduction; II. CD40 and Ligand Expression and Molecular Structure. 
505 8 |a III. Intracellular Signal Transduction through CD40IV. CD40-gp39 Functional Interactions; V. The Role of CD40 Signaling in B Lymphocyte Proliferation; VI. The Role of CD40 in Immunoglobulin Production; VII. The Role of CD40 in Germinal Center and Memory Cell Formation; VIII. Summary; References; Chapter 3. Human Immunodeficiency Virus Infection of Human Cells Transplanted to Severe Combined Immunodeficient Mice; I. Introduction; II. Description of Human-to-Mouse Xenograft Models; III. Human Immunodeficiency Virus; IV. HIV-1 Infection in the hu-PBL-SCID Model. 
505 8 |a v. HIV-1 Infection in the SCID-hu thy/liv ModelVI. Conclusions; References; Chapter 4. Lessons from Immunological, Biochemical, and Molecular Pathways of the Activation Mediated by IL-2 and IL-4; I. Introduction; II. Cell Surface Receptors for IL-2 and IL-4; III. From Nonreceptor Protein Tyrosine Kinases to Adaptor Molecules; IV. From Ras to the MAPK Pathway; V. From the GTP-Binding Protein Rho to Control of the Cytoskeleton; VI. Nuclear Transcription Factor NF-kB; VII. Target Genes in IL-2 Signals; VIII. The Counterpart of Protein Kinases: The Phosphoprotein Phosphatases. 
505 8 |a IX. Specific Signaling Molecules for IL-4, IL-9, IL-13, and Insulin ReceptorsX. Cooperation of the Three IL-2-Induced Signaling Pathways; XI. Concluding Remarks; References; Chapter 5. B Lymphocyte Development and Transcription Regulation in Vivo; I. Introduction; II. Transcription Regulation in Vivo; III. B Lymphocyte Development in Vivo in the Normal Mouse; IV. Transcription Factors in B Lymphocyte Genesis; V. Concluding Remarks; References; Chapter 6. Soluble Cytokine Receptors: Their Roles in Immunoregulation, Disease, and Therapy; I. Introduction; II. Regulation of Cytokine Activity. 
505 8 |a III. Cytokine Receptors: Membrane and Soluble FormsIV. Production of Soluble Cytokine Receptors; V. The Immunoregulatory Function of Soluble Cytokine Receptors; VI. The Properties of Soluble Cytokine Receptors and Relationship to Disease; VII. Soluble Cytokine Receptors and Therapy; VIII. Summary and Conclusions; References; Chapter 7. Cytokine Expression and Cell Activation in Inflammatory Arthritis; I. Introduction; II. The Inflammatory Synovial Environment; III. Assessment of Cytokine Expression and Activity in Synovitis; IV. Pro-inflammatory Cytokines and Growth Factors. 
650 0 |a Immunology. 
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700 1 |a Dixon, Frank J.  |q (Frank James),  |d 1920-2008. 
776 0 8 |i Print version:  |t Advances in immunology. Volume 63.  |d New York : Academic Press, �1996  |z 0120224631  |z 9780120224630  |w (OCoLC)35918481 
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