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Advances in immunology. Volume 60
This volume highlights the latest reviews of mechanisms and actions of the immune system and the host response to infection and inflammation. Key Features * Covers cytokine functioning as influenced by the Janus protein tyrosine kinase family * Explores immunodeficiencies, including: * Immunoglobuli...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
New York :
Academic Press,
�1995.
|
| Colección: | Advances in immunology.
|
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
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| 245 | 0 | 0 | |a Advances in immunology. |n Volume 60 |h [electronic resource] / |c edited by Frank J. Dixon. |
| 260 | |a New York : |b Academic Press, |c �1995. | ||
| 300 | |a 1 online resource (x, 388 pages) : |b illustrations. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Advances in Immunology ; |v v.60 | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 520 | |a This volume highlights the latest reviews of mechanisms and actions of the immune system and the host response to infection and inflammation. Key Features * Covers cytokine functioning as influenced by the Janus protein tyrosine kinase family * Explores immunodeficiencies, including: * Immunoglobulin deficiencies and B cells development * Glycosyl Phosphatidylinositol (GPI)-anchor and Paroxysmal Nocturnal Hemoglobinuria (PNH) * Investigates the links molecular pathology established between deficiencies in GPI-anchor synthesis and PNH * Includes the use of Multiple Antigen Peptides (MAPs) to induce protective immune response * Offers a timely update on Eosinophils' role in disease * Covers histology of Germinal center reaction of a spleen twelve days after primary immunization * Includes new research on cytotoxic T-lymphocytes * Presents the multiple roles of Nitric oxide (NO) in the inflammatory response. | ||
| 505 | 0 | |a Front Cover; Advances in Immunology, Volume 60; Copyright Page; Contents; Contributors; Chapter 1. The Janus Protein Tyrosine Kinase Family and Its Role in Cytokine Signaling; I. Introduction; II. Origins and Structure of the Janus Kinases; III. Janus Kinases Couple Cytokine Binding to Induction of Tyrosine Phosphorylation; IV. The Role of Receptor Dimerization/Oligomerization in Activation of Janus Kinases; V. Association of Jaks with Cytokine Receptors Occurs through the Membrane Proximal Domains; VI. Activation of the ras Signaling Pathway by Cytokine Receptors. | |
| 505 | 8 | |a VII. Cytokines Induce Increases in Phosphatidylinositol (PI)-3 Kinase ActivityVIII. Insulin-Receptor Substitute 1 (IRS-1) and 4PS: Signal Transducers Phosphorylated in Response to Cytokines; IX. Vav: A Common Substrate of Cytokine-Induced Tyrosine Phosphorylation; X. Signal Transducers and Activators of Transcription Stats: A Novel Family of Transcription Factors Identified in Interferon Signaling; XI. Stats: A Common Theme in Cytokine Signding; XII. Mechanisms of Stat Recruitment to Cytokine Receptor Complexes; XIII. Stat Proteins Regulate a Variety of Genes in Hematopietic Cells. | |
| 505 | 8 | |a XIV. Negative Regulation of Cytokine Signaling by Tyrosine PhosphatasesXV. Jaks and Stats in Other Receptor Systems; XVI. Summary and Conclusions; References; Chapter 2. X-Linked Agammaglobulinemia and Immunoglobulin Deficiency with Normal or Elevated IgM: Immunodeficiencies of B Cell Development and Differentiation; I. Introduction; II. B Cell Development and Differentiation; III. XLA: A Defect of B Cell Development; IV. HIGMX-1: A Defect of B Cell Differentiation; V. Conclusion and Future Prospects; References. | |
| 505 | 8 | |a Chapter 3. Defective Glycosyl Phosphatidylinositol Anchor Synthesis and Paroxysmal Nocturnal HemoglobinuriaI. Introduction; II. The GPI Anchor and the GPI-Anchored Proteins; III. Paroxysmal Nocturnal Hemoglobinuria (PNH); IV. Perspectives and Conclusions; References; Chapter 4. The Use of Multiple Antigen Peptides in the Analysis and Induction of Protective Immune Responses against Infectious Diseases; I. Multiple Antigen Peptides; II. MAPs as Immunogens in Protozoan Diseases; III. MAPS as Immunogens in Helminthic Diseases; IV. MAPS as Immunogens in Viral and Bacterial Diseases. | |
| 505 | 8 | |a V. MAPs as AntigensVI. Conclusions; References; Chapter 5. Eosinophils: Biology and Role in Disease; I. Biology of the Eosinophil; II. Eosinophils and Parasites; III. Eosinophils and Disease; IV. Final Conclusions; References; Chapter 6. In Situ Studies of the Germinal Center Reaction; I. Introduction; II. Histology of the Spleen; III. The Germinal Center Reaction; IV. Somatic Hypermutation, Selection, and the Generation of Immunological Memory; V. Germinal Centers and Other Microenvironments for Diversification; VI. Conclusions; References. | |
| 650 | 0 | |a Immunology. | |
| 650 | 2 | |a Allergy and Immunology |0 (DNLM)D000486 | |
| 650 | 4 | |a Allergy and immunology |v Periodicals. | |
| 650 | 4 | |a Allergy and immunology. | |
| 650 | 4 | |a Immunity. | |
| 650 | 4 | |a Immunologic diseases. | |
| 650 | 4 | |a Immunology |v Periodicals. | |
| 650 | 4 | |a Immunology. | |
| 650 | 6 | |a Immunologie. |0 (CaQQLa)201-0066630 | |
| 650 | 7 | |a MEDICAL |x Immunology. |2 bisacsh | |
| 650 | 7 | |a Immunology |2 fast |0 (OCoLC)fst00968006 | |
| 650 | 7 | |a Immunit�e. |2 fmesh | |
| 650 | 7 | |a Allergie et immunologie. |2 fmesh | |
| 700 | 1 | |a Dixon, Frank J. |q (Frank James), |d 1920-2008. | |
| 776 | 0 | 8 | |i Print version: |t Advances in immunology. Volume 60. |d New York : Academic Press, �1995 |z 0120224607 |z 9780120224609 |w (OCoLC)35009968 |
| 830 | 0 | |a Advances in immunology. | |
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| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00652776/60 |z Texto completo |