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Advances in cancer research. Volume 70
Volume 70 begins with two "Foundations in Cancer Research" articles, a staple of the Advances in Cancer Research series. The first article by Michael Stoker presents a review of some of the early advances made by cancer cell biology researchers. The second article by Emmanuel Farber descri...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
�1996.
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| Colección: | Advances in cancer research ;
70 |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Advances in Cancer Research, Volume 70; Copyright Page; Contents; Contributors to Volume 70; Chapter 1. Foundations in Cancer Research: Fundamentals of Cancer Cell Biology; I. Introduction; II. Antecedents; III. Autobiographical Note; IV. Foundations of Tissue Culture; V. Foundations of Cell Culture; VI. Clones; VII. The Immortals: Stable Cell Lines; VIII. The Mortals: Cell Strains; IX. Food for Cells in Culture; X. Growth Factors; XI. Short-Range Cell Interactions; XII. Junctional Communication; XIII. Cell and Substrate Adhesion; XIV. The Tumor Viruses; XV. Cell Fusion
- XVI. ConclusionReferences; Chapter 2. Foundations in Cancer Research the Step-By-Step Development of Epithelial Cancer: From Phenotype to Genotype; I. Cancer Development as Basic to Cancer Research; II. Patterns of Development of Epithelial Cancers; III. A Working Hypothesis; IV. The Phenotypes; V. The Genotypes; VI. The Challenge; References; Chapter 3. Genetics of the Nevoid Basal Cell Carcinoma Syndrome; I. Introduction; II. Clinicopathological Features of NBCCS; III. Genetics of NBCCS; IV. Strategies for Isolation of Candidate Genes; V. Discussion; References
- Chapter 4. Transforming Growth Factor-� System and Its Regulation by Members of the Steroid-Thyroid Hormone SuperfamilyI. Introduction; II. Transforming Growth Factor-�; III. Dual Effects of TGF-� on Cell Proliferation; IV. Regulation of Cell Differentiation by TGF-�; V. TGF-� in the Regulation of the Immune System; VI. The Steroid-Thyroid Hormone Superfamily; VII. Steroid Hormone Regulation of TGF-� Isoform Expression; VIII. Regulation of Plasminogen Activation by Steroids; IX. Summary; References; Chapter 5. c-Myc in the Control of Cell Proliferation and Embryonic Development
- I. IntroductionII. The c-myc Gene; III. Structural and Functional Features of the c-Myc Protein; IV. c-Myc as a Transcription Factor; V. c-Myc and Cell Proliferation; VI. c-Myc in Embryonic Development; VII. c-Myc and Differentiation; VIII. c-Myc and Apoptosis; References; Chapter 6. Identification of the Genes Encoding Cancer Antigens: Implications for Cancer lmmunotherapy; I. Introduction; II. Methodology; III. Human Melanoma Antigens Recognized by T Cells; IV. Cancer Therapies Based on the Molecular Identification of Cancer Antigens; References
- Chapter 7. The MEN II Syndromes and the Role of the ret Proto-oncogeneI. Introduction; II. The MEN II Syndromes; III. The ret Proto-oncogene; IV. Development of the Tissues Involved in MEN II, and Patterns of ret Expression; V. Speculations on How Different ret Mutations Result in the Associated Phenotypes and in Tumor Formation; VI. Other Events in Tumor Progression; VII. Animal Models of MEN II; VIII. Clinical Implications of the Identification of ret Mutations in MEN II; IX. Future Prospects; References; Index