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Progress in medicinal chemistry. 5 /
PROGRESS IN MEDICINAL CHEMISTRY 5.
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Butterworths,
1967.
|
| Colección: | Progress in medicinal chemistry ;
5 |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Progress in Medicinal Chemistry, Volume 5; Copyright Page; CONTENTS; Preface; CHAPTER 1. POLYPEPTIDE ANTIBIOTICS OF MEDICINAL INTEREST; 1. Introduction; 2. Classification of peptides; 3. Techniques of peptide chemistry; 4. Polypeptide antibiotics produced by B. brevis; 5. Peptide antibiotics pioduced by B. subtilis and B. licheniformis; 6. Polypeptide antibiotics produced by other strains of bacilli; 7. Polypeptide antibiotics produced by streptomyces; 8. Polypeptide antibiotics produced by fungi; 9. Polypeptide antibiotics isolated from different sources
- 10. Biosynthesis of polypeptide antibiotics11. Mechanism of action of polypeptide antibiotics; CHAPTER 2. NON-STEROIDAL ANTI-INFLAMMATORY DRUGS; 1. Introduction; 2. The nature and mechanism of inflammation; 3. Tests for anti-inflammatory activity; 4. Anti-inflammatory compounds; 5. Mode of action; 6. Uncoupling of oxidative phosphorylation; 7. Inhibition of hyaluronidase; 8. Stimulation of the adrenal cortex; 9. Chelation; 10. Hyperglycaemia; 11. Effects on immunological processes; CHAPTER 3. THE PHARMACOLOGY OF HEPARIN AND HEPARINOIDS; 1. Introduction
- 2. Complexing properties of heparin, heparinoids and mucopolysaccharides3. Biological reactions of heparin and heparinoids; 4. Anticoagulant activity; 5. Haemorrhage and thrombosis; 6. Chemical structure and biological activity; 7. Absorption, distribution and metabolism; 8. Toxicity; 9. Endogenous heparin and heparinoids; CHAPTER 4. THE HISTIDINE DECARBOXYLASES; 1. Introduction; 2. The measurement of histidine decarboxylase activity; 3. The substrate specificity of histidine decarboxylases; 4. The distribution of histidine decarboxylases
- 5. The mechanism of action of histidine decarboxylases6. Inhibition of histidine decarboxylation in vitro; 7. Inhibition of histidine decarboxylation in vivo; 8. Factors which modify the histidine decarboxylase activity of tissues; 9. The physiological function of histidine decarboxylases; 10. Concluding remarks; CHAPTER 5. PSYCHOT'ROPIC DRUGS AND NEUROHUMORAL SUBSTANCES IN THE CENTRAL NERVOUS SYSTEM; 1. Introduction; 2. The physiological background; 3. Humoral factors in the brain; 4. Classification and properties of the psychotropic drugs; 5. Psychotropic drugs and neurohumoral processes
- 6. ConclusionsCHAPTER 6. THE NITROFURANS; 1. Introduction to historical development; 2. Chemical and physical properties of nitrofuran compounds; 3. Synthesis of nitrofurans; 4. Toxicology, pharmacology and tolerancv; 5. Assays of nitrofurans; 6. Metabolism of nitrofurans; 7. Antibacterial properties in vitro; 8. Antibacterial properties in vivo; Addendum; Index