Drug-like properties : concepts, structure design and methods : from ADME to toxicity optimization /

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Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasin...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Kerns, Edward Harvel
Otros Autores: Di, Li
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Academic Press, �2008.
Colección:Drug Discovery Bundle.
Temas:
Pharmaceutical chemistry.
Drugs > Structure-activity relationships.
Drug development.
Drugs > Design.
Drugs > Side effects.
Pharmacokinetics.
Structure-activity relationships (Biochemistry)
Drug Design
Chemistry, Pharmaceutical
Drug Evaluation, Preclinical
Drug-Related Side Effects and Adverse Reactions
Pharmaceutical Preparations > metabolism
Pharmacokinetics
Structure-Activity Relationship
Chimie pharmaceutique.
M�edicaments > Relations structure-activit�e.
M�edicaments > D�eveloppement.
M�edicaments > Conception.
M�edicaments > Effets secondaires.
Pharmacocin�etique.
Relations structure-activit�e (Biochimie)
MEDICAL > Drug Guides.
MEDICAL > Pharmacology.
MEDICAL > Pharmacy.
MEDICAL > Nursing > Pharmacology.
Drugs > Side effects
Drug development
Drugs > Design
Drugs > Structure-activity relationships
Pharmaceutical chemistry
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Preface; Introductory Concepts; Physicochemical Properties; Disposition, Metabolism and Safety; Methods; Specific Topics; Answers to Problems; Appendix I: General References; Appendix II: Glossary.

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