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Advances in immunology. Volume 74 /
Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and auth...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
�2000.
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| Colección: | Advances in immunology.
|
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Front Cover; Advances in Immunology, Volume 74; Copyright Page; Contents; Contributors; Chapter 1. Biochemical Basis of Antigen-Specific Suppressor T Cell Factors: Controversies and Possible Answers; I. Introduction; II. Historical Background; III. Controversial Issues on Antigen-Specific TsF and Possible Answers; IV. Possible Roles of GIF as a Subunit of TsF; V. Discussion and Summary; References; Chapter 2. The Role of Complement in B Cell Activation and Tolerance; I. Introduction; II. Complement C3 Alters Fate of Antigen; III. Complement Enhancement of Humoral Immunity.
- IV. Negative Selection of Self-Reactive B CellsV. Complement Deficiency and SLE; VI. Summary; References; Chapter 3. Receptor Editing in B Cells; I. Introduction; II. Receptor Selection versus Clonal Selection; III. Antigen Receptor Gene Assembly by V(D)J Recombination; IV. Recombination Signals and the 12/23 Rule; V. Ig Genes of Mouse and Man; VI. Secondary Rearrangements; VII. Recombinational Accessibility; VIII. Quasi-ordered Rearrangements; IX. Allelic Exclusion; X. Mechanisms of Allelic Exclusion; XI. Ig-L-Chain Allelic Exclusion.
- XII. Receptor Editing Monitored in Vivo in Transgenic Models of Immune ToleranceXIII. Analysis of Receptor Editing in Gene-Targeted Antibody Gene Mice; XIV. Central B Cell Tolerance Is Associated with Developmental Block; XV. Locus Specificity of B Cell Receptor Editing; XVI. Developmental Stage Specificity of Receptor Editing; XVII. A Role for Receptor Editing in Receptor Diversification?; XVIII. Editing in Mature, Antigen-Reactive B Cells: Receptor Revision; XIX. Locus Specificity of Receptor Revision; XX. Potential Functions of Receptor Revision.
- XXI. Problems with the Receptor Selection ConceptXXII. Conclusion; References; Chapter 4. Chemokines and Their Receptors in Lymphocyte Traffic and HIV Infection; I. Introduction; II. Expanding Functional Implications of Chemokines; III. Chemokines and Chemokine Receptors in Lymphocytes; IV. Chemokine-Mediated Signal Transduction; V. HIV Infection; References; Chapter 5. Escape of Human Solid Tumors from T-Cell Recognition: Molecular Mechanisms and Functional Significance; I. Introduction; II. Tumor Cell-Escape Mechanisms; III. Inadequacy of Tumor Cells as Targets.
- IV. Potential Role of HLA Class I Polymorphism in Tumor Cell EscapeV. Inhibitory Signals Provided by the Tumor Microenvironment; VI. Inadequate Immunogenicity of the Tumor Microenvironment; VII. Escaping Escape Mechanisms: Possible Immunological Alternatives; References; Chapter 6. The Host Response to Leishmania Infection; I. Introduction; II. The Parasite; III. The Host's Innate Response; IV. The Host's Adaptive Immune Response; V. Persistence; VI. Genetic Background of Resistance and Susceptibility; VII. Concluding Remarks; References; Index; Contents of Recent Volumes.