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Medicinal chemistry of anticancer drugs /

Antitumour chemotherapy is nowadays a very active field of research, and a huge amount of information on the topic is generated every year. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book addresses the need for an updated treatment from the point o...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Avenda�no, Carmen
Otros Autores: Men�endez, J. Carlos (Jos�e Carlos)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Elsevier, 2008.
Edición:1st ed.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • 1. Introduction to anticancer chemotherapy
  • 2. Antimetabolites
  • 3. Anticancer drugs that inhibit hormone action
  • 4. Anticancer drugs acting via radical species. Photosensitizers and photodynamic therapy of cancer.
  • 5. DNA alkylating agents
  • 6. Alkylating and non-alkylating compounds interacting with the DNA minor groove.
  • 7. DNA intercalation and inhibition of topoisomerases
  • 8. Anticancer drugs targeting tubulin and microtubules
  • 9. Drugs targeting signaling pathways for tumour cell growth and proliferation
  • 10. Other approaches to targeted therapy
  • 11. Drug targeting in anticancer chemotherapy
  • 12. Resistance to antitumour agents and drugs that modulate it
  • 13. Cancer chemoprevention.
  • Introduction
  • Antimetabolites
  • Anticancer drugs that inhibit hormone action
  • Anticancer drugs acting via radical species, photosensitizers and photodynamic therapy of cancer
  • DNA alkylating agents
  • Alkylating and non-alkylating compounds interacting with the DNA minor groove
  • DNA intercalators and topoisomerase inhibitors
  • Anticancer drugs targeting tubulin and microtubules
  • Drugs that inhibit signalling pathways for tumor cell growth and proliferation
  • Other approaches to targeted therapy
  • Drug targeting in anticancer chemotherapy
  • Drugs that modulate resistance to antitumor agents
  • Cancer chemoprevention.