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Advances in immunology. Volume 12 /

ADVANCES IN IMMUNOLOGY VOLUME 12.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Dixon, Frank J. (Frank James), 1920-2008, Kunkel, Henry G., 1916-1983
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York ; London : Academic Press, �1970.
Colección:Advances in immunology.
Temas:
Acceso en línea:Texto completo
Texto completo
Tabla de Contenidos:
  • Front Cover; Advances in Immunology, Volume 12; Copyright Page; Contents; List of Contributors; Preface; Contents of Previous Volumes; Chapter 1. The Search for Antibodies with Molecular Uniformity; I. Introduction; II. Immunoglobulin Heterogeneity and Antibody Properties Indicative of Limited Heterogeneity; III. Human Antibodies with Restricted Heterogeneity; IV. Experimental Generation of Antibodies with Restricted Heterogeneity; V. Myeloma Protein and Paraproteins with Antibody Activity; VI. Discussion and Summation; References; Chapter 2. Structure and Function of?M Macroglobulins.
  • I. IntroductionII. Isolation and Storage of Macroglobulins; III. Structure of Mammalian Macroglobulins; IV. Subunits, Polypeptide Chains, and Proteolytic Fragments; V. Low Molecular Weight Macroglobulin-Like Proteins; VI. Functional Properties of Macroglobulins; VII. Genetic Basis of Macroglobulin Structure; VIII. Biosynthesis and Metabolism of Macroglobulins; IX. Macroglobulin-Like Proteins from Nonmammalian Species; X. Role of Macroglobulins in the Immune Response; XI. Prospects; References; Chapter 3. Transplantation Antigens; I. Introduction.
  • II. Extraction and Solubilization of Transplantation AntigensIII. Physical and Chemical Nature of Transplantation Antigens; IV. Biological Activity of Extracted Transplantation Antigens; V. Perspectives; VI. Summary; References; Chapter 4. The Role of Bone Marrow in the Immune Response; I. Introduction; II. A Brief Survey of the Techniques Used for the Detection of Immuno- competent Cells; III. Bone Marrow as a Source of Immunocompetent Cells; IV. Cells Involved in the Humoral Immune Response; V. Cell Interactions Resulting in the Induction of the Immune Response.
  • Vl. Effects of Irradiation on the Immune ResponseVII. Cells Involved in Cell-Mediated Immunity; VIII. Cells Affected in Immunological Tolerance; IX. Bone Marrow Transplantation-Application; X. Conclusions; References; Chapter 5. Cell Interaction in Antibody Synthesis; I. Introduction; II. Two Universes of Immunocompetent Cells; III. The Adherent Cell; IV. Antigenic Competition; V. Enhancing Effect of Multiple Antigenic Determinants; VI. Enhancing and Suppressive Effects of Passively Administered Antibody; VII. Discussion and Speculations; References.
  • Chapter 6. The Role of Lysosomes in Immune ResponsesI. Introduction; II. Processing of Antigen by the Vacuolar System; III. Mediators of Tissue Injury Found in Lysosomes; IV. Lysosomes in Four Types of Immune Injury; References; Chapter 7. Molecular Size and Conformation of Immunoglobulins; I. Introduction; II. Molecular Size of Immunoglobulins and Subunits; III. Conformation of Immunoglobulins and Subunits; IV. Recovery of Native Conformation Following Chain Dissociation and Unfolding; V. Conclusions; References; Author Index; Subject Index.