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Vitamin K /
First published in 1943, VITAMINS AND HORMONES is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, VITAMINS AND HORMONES cont...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; London :
Elsevier,
2008.
|
| Colección: | Vitamins and hormones ;
v. 78. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Cover; Contents; Contributors; Preface; Chapter 1: Determinants of Vitamin K Status in Humans; I. Introduction; II. Assessment of Vitamin K Status; III. Nongenetic Determinants; IV. Genetic Determinants; V. Conclusions and Future Directions; Acknowledgments; References; Chapter 2: VKORC1 and the Vitamin K Cycle; I. Vitamin K Cycle: Limiting Step of Carboxylation; II. VKOR: Is It a Complex?; III. VKORC1 in Clinical Practice; IV. Conclusion; Acknowledgment; References; Chapter 3: The Vitamin K Cycle; I. Introduction; II. Vitamin K Biosynthesis; III. Vitamin K Cycle.
- IV. Physiological Role of Vitamin K Dependent ProteinsV. Clinical Phenotypes Related to the Vitamin K Pathway in Man; VI. Conclusions and Perspectives; Acknowledgments; References; Chapter 4: Structure, Function, and Mechanism of Cytosolic Quinone Reductases; I. Introduction; II. Quinone Reductase Type 1; III. Quinone Reductase Type 2; IV. Disclaimer; References; Chapter 5: Quinone Oxidoreductases and Vitamin K Metabolism; I. Vitamin K and Vitamin K Cycle; II. Quinone Oxidoreductases; III. Quinone Oxidoreductases and Reduction of Vitamin K to Hydroquinone.
- IV. Quinone Oxidoreductases and Metabolic Detoxification or Activation of Vitamin KV. Quinone Oxidoreductases and Anticancer Effects of Vitamin K; VI. Future Perspectives; Acknowledgments; References; Chapter 6: Structure and Function of Vitamin K Epoxide Reductase; I. Introduction; II. Purification of VKOR; III. Mechanism of Vitamin K Epoxide Reduction Catalyzed by VKOR; IV. Identification of the Active Site of VKOR; V. Warfarin Inhibition of VKOR; VI. Membrane Topology of VKOR; VII. Conclusion; References; Chapter 7: Vitamin K Dependent Carboxylation; I. Vitamin K-Dependent Protein Function.
- II. Vitamin K FormsIII. Mechanism of Carboxylation; IV. Functional Regions of the Carboxylase; V. Vitamin K Reduction Is Required for Carboxylation in Tissue; VI. Carboxylation Interfaces with Secretion; VII. The Capacity of Vitamin K-Dependent Protein Carboxylation Is Limited in Cultured Cells; VIII. Summary; References; Chapter 8: Vitamin K-Dependent gamma-Glutamylcarboxylation: An Ancient Posttranslational Modification; I. Introduction; II. Reviews; III. gamma-Carboxylation Reaction; IV. Vitamin K Cycle; V. Mechanism of gamma-Carboxylation.
- VI. Proposed Topology of gamma-Glutamyl CarboxylaseVII. Substrate Recognition (Propeptide); VIII. Structure-Function Relationship; IX. Expression of GGCX During Development; X. Gla-Containing Proteins and gamma-Carboxylase in Urochordate; XI. Drosophila gamma-Glutamyl Carboxylase; XII. gamma-Carboxylated Peptides in Conus; XIII. Conus gamma-Glutamyl Carboxylase; XIV. Future Prospects; Acknowledgments; References; Chapter 9: Vitamin K-De pendent Actions of Gas6; I. Introduction; II. Gas6 Structure; III. Cellular Effects of Gas6.