Vitamins and hormones : advances in research and applications. Volume 62 /

Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board reflects expertise in the fields of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Every volume contains comprehensive reviews by leading contributors.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Litwack, Gerald
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego, Calif. : Academic Press, �2001.
Colección:Vitamins and hormones ; v. 62.
Temas:
Vitamins > Research.
Vitamins > Research
Acceso en línea:Texto completo
Texto completo
Tabla de Contenidos:
  • Front Cover; VITAMINS AND HORMONES; Copyright Page; Contents; Preface; Chapter 1. Green Tea: Biochemical and Biological Basis for Health Benefits; I. Introduction; II. Catechins and Other Constituents of Green Tea; III. Structure, Pharmacology, and Metabolism of Catechins; IV. Chemical and Biochemical Properties of Catechins; V. Biological Activity of Green Tea Catechins; VI. Molecular and Cellular Bases for Biological Effects of Catechins; VII. Epilog; References; Chapter 2. Proteins Regulating the Biosynthesis and Inactivation of Neuromodulatory Fatty Acid Amides
  • I. Fatty Acid Amides as Endogenous Signaling MoleculesII. The Biosynthesis of Fatty Acid Amides; III. The Enzymatic Inactivation of Fatty Acid Amides; IV. Transport of Fatty Acid Amides; V. Conclusions and Future Challenges; References; Chapter 3. Three-Dimensional Organization of the Aquaporin Water Channel: What Can Structure Tell Us about Function?; I. Movement of Water across the Membrane-Discovery of Aquaporin-1; II. Mammalian Aquaporins and Their Transport Function; III. Investigations of Amino Acid Residues Involved in Solute Transport in Aquaporins
  • IV. Structural Studies of AquaporinsV. Unresolved Questions and Future Directions; References; Chapter 4. Cytostatic p21 G Protein-Activated Protein Kinase?-PAK; I. Background; II. Comparison of PAK Proteins; III. Autophosphorylation and Activation of?-PAK; IV.?-PAK Has Cytostatic Activity; V. Activation of?-PAK in Response to Stress; VI. The Individual Roles of?-PAK and SAPK/p38 in the Stress Response; VII. Substrates for?-PAK; VIII. Working Model-A Role for?-PAK as a Master Switch; IX. Conclusions and Remaining Questions; References; Chapter 5. Androgen Receptors and Their Biology
  • I. Mechanism of Androgen ActionII. Sexual Development; III. Androgen Receptors and Disease; IV. Androgen Action and Other Diseases; V. Conclusion; References; Chapter 6. Transcriptional Activation of Genes by 17�-Estradiol through Estrogen Receptor-Sp1 Interactions; I. Introduction; II. Transcriptional Activation through Sp1(N)xERE 1/2 and Sp1(N)xERE Motifs; III. Transcriptional Activation by E2 through GC-Rich Sites; IV. E2-Responsive Genes with Functional GC-Rich Promoter Elements; V. ERa/Sp1 Activation by Growth Factors
  • VI. ERa/Sp1 vs ER�/Sp1 Action and Effects of Ligand Structure and Cell ContextVII. Summary; References; Chapter 7. Drug Discovery and the Intracellular Receptor Family; I. The History of Intracellular Receptor Ligands as Drugs; II. Diseases in Which Intracellular Receptors Play a Role; III. Intracellular Receptor Ligands with Therapeutic Utility (Agonists and Antagonists); IV. Partial Agonists of Intracellular Receptors; V. Ligand Discovery; VI. Direct Measures of Intracellular Receptor Conformation; VII. Indirect Methods of Conformation Determination; VIII. Cofactor-Receptor Interactions

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