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Selected topics in the history of biochemistry - personal recollections VII /

This book is the latest volume in a highly successful series within Comprehensive Biochemistry and provides a historical and autobiographical perspective of the development of the field through the contributions of leading individuals who reflect on their careers and their impact on biochemistry. Th...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Semenza, G., 1928-, Turner, A. J. (Anthony John), 1947-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Oxford : Elsevier, 2003.
Colección:Comprehensive biochemistry. Section VII: History of biochemistry ; v. 42.
Temas:
Acceso en línea:Texto completo
Texto completo
Texto completo
Tabla de Contenidos:
  • Front Cover; Comprehensive Biochemistry; Copyright Page; CONTENTS; Preface to Volume 42; Contributors to this Volume; Chapter 1. Fifty Years in the World of Proteins; Origins; Cohn and Edsall; My First Project in Protein Science; The Invention of Polymer Science?; Macromolecules:Theoretical Research with J.G. Kirkwood; Antibodies; Genetic Basis forAntibody Diversity; Subunits and Allosterism; Micelles and Membranes; Membrane Proteins; Philip Handler and the Einstein Statue; Eastman Professor at Oxford; Popular Writing: Travel Books; Historical Perspective; References
  • Chapter 2. Proteins, Life and EvolutionAbstract; Introduction; CV of the Guide Through the Text; Early Days, Scientific Fathers; Cambridge, the Mecca at the Start; Development of Protein Sequence Analysis; SeparationTechniques and Continued Progress; Amino Acid Analysis, Complementary Approaches, and Further Development; Correlationwith 3-D Structures; Developments in Molecular Genetics; Molecular Evolution: Development from Early "Diagonals," over the Atlas Issues, to Bioinformatics; Mass Spectrometry; Present Situation, Including Comments on Karolinska, Nobel, and Funding
  • Chapter 5. RNA Enzymology and BeyondGrowing Up; Weizmann Institute of Science; St. Louis: Polynucleotide Phosphorylase; Isolation of High Molecular Weight Ribosomal RNA; The Single-Stranded Nature of rRNA; Early Studies on the Secondary Structure of RNA; tRNA Regulation; PNPase Research Applications; Differentiation of Artemia salina Cysts; Establishment of the Department of Neurobiology; Microtubule Proteins; Promoting International Links; References; Chapter 6. Some Selected Recollections from a Life with Biochemistry; Introduction; StudentYears at the University of Copenhagen
  • Experiments with PenicillinPupil of Herman Kalckar and Experiments with Xanthine Oxidase; Excursion to Two European Strongholds in Biochemistry; Ribose 1,5-Diphosphate; National Institutes of Health 1952-1953; Back in Copenhagen; Cancer Research; Experiments with 2' -Deoxyadenosine; Experiments with 3' -Deoxyadenosine; Back to the University of Copenhagen; Experiments with other Congeners of Adenosine; Experiments with DNA Polymerase from E. coli; Ribonucleotides Again; Regulation of Cellular Content of Nucleoside Triphosphates; Conclusion; References