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Advances in immunology. Volume 78 /

Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that constitue immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and aut...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Dixon, Frank J. (Frank James), 1920-2008, Alt, Frederick W.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego [Calif.] : Academic Press, �2001.
Colección:Advances in immunology ; 78.
Temas:
Acceso en línea:Texto completo
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Tabla de Contenidos:
  • Front Cover; Advanced in Immunology; Copyright Page; Contents; Contributors; Chapter 1. Toll-like Receptors and Innate Immunity; I. Introduction; II. Toll Receptors in Drosophila Development; III. Toll Receptors in Innate Immunity of Drosophila; IV. Mammalian IL-1R-Signaling Pathway. Its Similarity with Drosophila Toll Signaling; V. Discovery of Toll-like Receptors in Mammals; VI. LPS and Its Binding Molecules; VII. Intracellular Events Following LPS Stimulation; VIII. Nuclear Factors Activated by LPS; IX. TLR4 and LPS Signaling; X. Role of MyD88 in LPS Signaling
  • XI. MyD88-Dependent and -Independent Pathways in LPS SignalingXII. LPS Internalization; XIII. Species Differences in LPS Response; XIV. Taxol and LPS; XV. LPS Tolerance; XVI. TLR2 and LPS Signaling; XVII. Recognition of Microbial Cell Wall Components by TLRs; XVIII. Toll-like Receptors and Host Resistance to Microbial Infection; XIX. Conclusion; References; Chapter 2. Chemokines in Immunity; I. Introduction; II. Chemokine Superfamily; III. Migratory Properties of Lymphocytes and Dendritic Cells; IV. Primary Lymphoid Organs and Chemokines; V. Secondary Lymphoid Organs and Chemokines
  • VI. Effector/Memory Cells and ChemokinesVII. Dendritic Cells and Chemokines; VIII. Concluding Remarks; References; Chapter 3. Attractions and Migrations of Lymphoid Cells in the Organization of Humoral Immune Responses; I. Introduction; II. Structures of Chemokines and Their Receptors; III. Rules to Understand Receptor-Ligand Interaction and Migration in Vivo; IV. The Generation of Cells Involved in the Humoral Defense against Foreign Invaders; V. The Population of Secondary Lymphoid Organs by Lymphoid Cells; VI. Compartmental Homing within Secondary Lymphoid Organs
  • VII. Cellular Traffic Leading to a Humoral Immune Response. Finding the Right PartnerVIII. Migration of Effector and Memory T and B Cells; IX. Possible Clinical Relevance of the ABCD Chemokines; X. Future Perspectives; References; Chapter 4. Factors and Forces Controlling V(D)J Recombination; I. Introduction; II. Basic Features of V(D)J Recombination; III. Forces Controlling Chromatin Structure and Accessibility; IV. Cis-Acting Elements and the Assembly of Antigen Receptor Loci; V. The Factors; VI. The Two Substrate Problem; VII. Models; References
  • Chapter 5. T Cell Effector Subsets. Extending the Th1/Th2 ParadigmI. Introduction; II. T Cell Effector Subsets; III. What Determines Effector T Cell Differentiation?; IV. Transcription Factors for T Cell Differentiation; V. The Link between Chemokine Receptors and T Cell Effector Function; VI. Cell Surface and Costimulatory Molecules That Distinguish T Cell Effector Functions; VII. Microarrays for the Identification of T Cell Subset Expressed Genes; VIII. Conclusions; References; Chapter 6. MHC-Restricted T Cell Responses against Posttranslationally Modified Peptide Antigens; I. Introduction