Tabla de Contenidos:
  • 1. Receptors: Topology, organization, and function
  • 2. Adrenergic and muscarinic cholinergic receptors
  • 3. 5-Hydroxytryptamine receptors
  • 4. Dopamine receptors
  • 5. GABAA receptors in the central nervous system
  • 6. Excitatory amino acid receptors
  • 7. Substance P
  • 8. Pharmacology and molecular biology of opioid receptors
  • 9. Inositol 1,4,5-trisphosphate receptors
  • 10. The LDL receptor
  • 11. Angiotensin II peptide hormone receptors: Structure/function correlates
  • 12. Melanocortin receptors
  • 13. Pharmacology in the critically III
  • 14. Principles of drug metabolism
  • 15. Adrenergic drugs
  • 16. Cholinergic Agents
  • 17. Rational methods for site-directed drug design
  • 18. The advantages of liposome-based gene therapy: A comparison of viral versus liposome-based gene delivery
  • 19. The kallikrein-kinin-kininogen system
  • 20. Cellular responses to eicosanoids: Molecular biology of eicosanoid receptors
  • 21. Nitric oxide as a bioregulator
  • 22. Medicinal Chemistry of steroids
  • 23. The influence of anabolic steroids on muscular strength
  • 24. Genomic pharmacology: From receptor internalization to nuclear translocation of third messengers
  • 25. Cardiac glycosides
  • 26. Antiarrhythmic drugs
  • 27. The tissue specificity of calcium antagonists
  • 28. Mode of action of angiotensin converting enzyme inhibitors
  • 29. Mode of action of lipid-lowering drugs
  • 30. The physiologic basis of diuretic drug action and synergism
  • 31. Insulin and hypolycemic drugs
  • 32. Hypnotics and anti-anxiety agents
  • 33. Accurate diagnosis and drug selection in patients with chronic pain
  • 34. Leukotrienes
  • 35. Anti-inflammatory drugs: Mechanisms of action
  • 36. Treatment of gout and hyperuricemia
  • 37. Idiosyncratic drug reactions
  • 38. Treatment of convulsive disorders
  • 39. General anesthetics
  • 40. Cellular mechanisms of anesthesia
  • 41. Alcohol and alcoholism
  • 42. The mode of action and metabolism of vitamin A
  • 43. Vitamin A binding proteins
  • 44. Biochemistry of the visual cycle
  • 45. Vitamin B12
  • 46. Vitamin C
  • 47. The prehormone vitamin D
  • 48. Vitamin E
  • 49. Vitamin K: Metabolic functions, mechanism of action, and human requirements
  • 50. Selenium in nutrition and therapeutics
  • 51. The dependence syndrome concept for alcohol and drug abuse
  • 52. Opioid tolerance and dependence
  • 53. Activation mechanisms of chemical toxicity
  • 54. Mechanisms of cell toxicity
  • 55. The blood-brain barrier as a protector against neurotoxic agents
  • 56. Chelating agents as antidotes of metal poisoning.