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070828s2000 xx o 000 0 eng d |
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|a OPELS
|b eng
|e pn
|c OPELS
|d OPELS
|d OCLCQ
|d IDEBK
|d OCLCQ
|d OCLCF
|d NRU
|d UKDOC
|d OCLCQ
|d UIU
|d TFW
|d OCLCQ
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|a 704434944
|a 823107303
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|a 1281019445
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|a 9781281019448
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|a 9780080526775
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|a 0080526772
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|z 9780762305933
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|z 0762305932
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|a (OCoLC)166344406
|z (OCoLC)704434944
|z (OCoLC)823107303
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|a RS400
|b .A35eb v. 5
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|a MF
|2 bicssc
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|a 615/.19
|2 22
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|a Advances in medicinal chemistry.
|n Volume 5.
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260 |
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|a [Place of publication not identified] :
|b Elsevier Science,
|c 2000.
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300 |
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|a 1 online resource
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
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|2 rdacarrier
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|a Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussing on neuroregenerative applications in the central nervous system. In Chapter 2, there is an overview of the development of a potent analgesic compound that works via modulation of neuronal nicotinic acetylcholine receptors. In Chapter 3, there is a description of dopamine D-2 autoreceptor partial agonists as potential therapy for the treatment of schizophrenia. In Chapter 4, there is a summary of the successful program in which potent non-peptide inhibitors of HIV protease from the AIDS virus were developed.
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|a Preface. Immunophilins: the next generation. Discovery of ABT-594 and related neuronal nicotinic acetylcholine receptor modulators as analgesic agents: medicinal chemistry and biology. Discovery and preclinical evaluation of novel dopamine partial agonists as antipsychotic agents. Nonpeptide inhibitors of HIV protease.
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|a Print version record.
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650 |
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|a Pharmaceutical chemistry.
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650 |
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|a Chemistry, Pharmaceutical
|0 (DNLM)D002626
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650 |
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|a Chimie pharmaceutique.
|0 (CaQQLa)201-0028674
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650 |
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|a Pharmaceutical chemistry.
|2 fast
|0 (OCoLC)fst01060115
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700 |
1 |
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|a Reitz, Allen Bernard,
|d 1956-
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700 |
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|a Dax, S. L.
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776 |
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|i Print version:
|a Reitz, A.B.
|t Advances in Medicinal Chemistry, Volume 5.
|d Burlington : Elsevier, �1999
|z 9780762305933
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856 |
4 |
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|u https://sciencedirect.uam.elogim.com/science/book/9780762305933
|z Texto completo
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