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Advances in medicinal chemistry. Volume 5.

Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussi...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Reitz, Allen Bernard, 1956-, Dax, S. L.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: [Place of publication not identified] : Elsevier Science, 2000.
Temas:
Acceso en línea:Texto completo

MARC

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520 |a Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussing on neuroregenerative applications in the central nervous system. In Chapter 2, there is an overview of the development of a potent analgesic compound that works via modulation of neuronal nicotinic acetylcholine receptors. In Chapter 3, there is a description of dopamine D-2 autoreceptor partial agonists as potential therapy for the treatment of schizophrenia. In Chapter 4, there is a summary of the successful program in which potent non-peptide inhibitors of HIV protease from the AIDS virus were developed. 
505 0 |a Preface. Immunophilins: the next generation. Discovery of ABT-594 and related neuronal nicotinic acetylcholine receptor modulators as analgesic agents: medicinal chemistry and biology. Discovery and preclinical evaluation of novel dopamine partial agonists as antipsychotic agents. Nonpeptide inhibitors of HIV protease. 
588 0 |a Print version record. 
650 0 |a Pharmaceutical chemistry. 
650 2 |a Chemistry, Pharmaceutical  |0 (DNLM)D002626 
650 6 |a Chimie pharmaceutique.  |0 (CaQQLa)201-0028674 
650 7 |a Pharmaceutical chemistry.  |2 fast  |0 (OCoLC)fst01060115 
700 1 |a Reitz, Allen Bernard,  |d 1956- 
700 1 |a Dax, S. L. 
776 0 8 |i Print version:  |a Reitz, A.B.  |t Advances in Medicinal Chemistry, Volume 5.  |d Burlington : Elsevier, �1999  |z 9780762305933 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780762305933  |z Texto completo