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Advances in medicinal chemistry. Volume 3.

Volume 3 of Advances in Medicinal Chemistry is comprised of four chapters on diverse aspects of medicinal chemistry. Chapter 1 presents an account of a research program which was started to discover a novel antipsychotic agent with minimal side effects for the treatment, principally, of schizophreni...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Maryanoff, B. E., Maryanoff, C. A.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: [Place of publication not identified] : Elsevier Science, 1995.
Temas:
Acceso en línea:Texto completo
Descripción
Sumario:Volume 3 of Advances in Medicinal Chemistry is comprised of four chapters on diverse aspects of medicinal chemistry. Chapter 1 presents an account of a research program which was started to discover a novel antipsychotic agent with minimal side effects for the treatment, principally, of schizophrenia. Chapter 2 relates an account on the discovery of novel antithrombotic drugs based on the RGD motif through a rational design approach. Chapter 3 presents the medicinal chemistry and preclinical development surrounding sertraline, a very important serotonin reuptake drug for the treatment of endogenous depression. Finally, Chapter 4 gives a summary of a series of boronic acid-based immunosuppressants that operate via inhibition of dipeptidypeptidase IV.
Descripción Física:1 online resource