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Gene therapy methods /
This volume in the prestigious Methods in Enzymology series discusses methods currently used in preclinical and clinical gene therapy. Subjects covered in this book, such as the use of adeno-associated virus delivery for treatment of Parkinson's disease, are topical and are presented in the met...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, Calif. :
Academic Press,
�2002.
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| Colección: | Methods in enzymology ;
volume 346. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo Texto completo |
Tabla de Contenidos:
- Chapter 1. Gene Therapy for Hypertension: The Preclinical Data; Chapter 2. Oligonucleotide-Mediated Site-Directed Gene Repair; Chapter 3. Stabilized Plasmid-Lipid Particles: A Systemic Gene Therapy Vector; Chapter 4. Enhancing Direct in Vivo Transfection with Nuclease Inhibitors and Pulsed Electrical Fields; Chapter 5. Hydrodynamics-Based Transfection: Simple and Efficient Method for Introducing and Expressing Transgenes in Animals by Intravenous Injection of DNAChapter 6. Bioplex Technology: Novel Synthetic Gene Delivery System Based on Peptides Anchored to Nucleic Acids; Chapter 7. Surgical Procedures for Intravascular Delivery of Plasmid DNA to Organs; Chapter 8. Direct Gene Transfer into Mouse Heart; Section II: Adenovirus; Chapter 9. Myoblast-Mediated Gene Transfer for Therapeutic Angiogenesis; Chapter 10. Use of Phage Display to Identify Novel Peptides for Targeted Gene Therapy; Chapter 11. Helper-Dependent Adenoviral VectorsChapter 12. Gene Transfer Methods for Transplantation; Chapter 13. Generation and Growth of Gutted Adenoviral Vectors; Chapter 14. Adenovirus-Mediated Gene Transfer for Cardiovascular and Renal Diseases; Chapter 15. Gene Transfer to Blood Vessels Using Adenoviral Vectors; Chapter 16. Rearrangements in Adenoviral Genomes Mediated by Inverted Repeats; Chapter 17. High-Capacity, Helper-Dependent, "Gutless" AdenoviralVectors for Gene Transfer into Brain; Chapter 18. Gene Therapy Methods in Cardiovascular Diseases; Section III: Adeno-Associated Virus; Chapter 19. Gene Delivery to Cardiac MuscleChapter 20. Recombinant AAV-Mediated Gene Delivery Using Dual Vector Heterodimerization; Chapter 21. Designing and Characterizing Hammerhead Ribozymes for Use in AAV Vector-Mediated Retinal Gene Therapies; Chapter 22. Adeno-Associated Viral Vector-Mediated Gene Therapy of Ischemia-Induced Neuronal Death; Chapter 23. Recombinant Adeno-Associated Viral Vector Production Using Stable Packaging and Producer Cell Lines; Chapter 24. Streamlined Large-Scale Production of Recombinant Adeno-Associated Virus (rAAV) Vectors; Section IV: Lentivirus; Chapter 25. Gene Transfer to the Brain Using Feline Immunodeficiency Virus-Based Lentivirus VectorsChapter 26. Generation of HIV-1 Derived Lentiviral Vectors; Chapter 27. Design, Production, Safety, Evaluation, and Clinical Applications of Nonprimate Lentiviral Vectors; Chapter 28. Gene Transfer to Airway Epithelia Using Feline Immunodeficiency Virus-Based Lentivirus Vectors; Chapter 29. Transduction of a Gene Expression Cassette Using Advanced Generation Lentiviral Vectors; Chapter 30. Construction, Purification, and Characterization of Adenovirus Vectors Expressing Apoptosis- Inducing Transgenes