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Gene therapy methods /

This volume in the prestigious Methods in Enzymology series discusses methods currently used in preclinical and clinical gene therapy. Subjects covered in this book, such as the use of adeno-associated virus delivery for treatment of Parkinson's disease, are topical and are presented in the met...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Phillips, M. Ian (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego, Calif. : Academic Press, �2002.
Colección:Methods in enzymology ; volume 346.
Temas:
Acceso en línea:Texto completo
Texto completo
Texto completo

MARC

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245 0 0 |a Gene therapy methods /  |c edited by M. Ian Phillips. 
260 |a San Diego, Calif. :  |b Academic Press,  |c �2002. 
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490 1 |a Methods in enzymology,  |x 0076-6879 ;  |v v. 346 
504 |a Includes bibliographical references and indexes. 
505 0 |a Chapter 1. Gene Therapy for Hypertension: The Preclinical Data; Chapter 2. Oligonucleotide-Mediated Site-Directed Gene Repair; Chapter 3. Stabilized Plasmid-Lipid Particles: A Systemic Gene Therapy Vector; Chapter 4. Enhancing Direct in Vivo Transfection with Nuclease Inhibitors and Pulsed Electrical Fields; Chapter 5. Hydrodynamics-Based Transfection: Simple and Efficient Method for Introducing and Expressing Transgenes in Animals by Intravenous Injection of DNAChapter 6. Bioplex Technology: Novel Synthetic Gene Delivery System Based on Peptides Anchored to Nucleic Acids; Chapter 7. Surgical Procedures for Intravascular Delivery of Plasmid DNA to Organs; Chapter 8. Direct Gene Transfer into Mouse Heart; Section II: Adenovirus; Chapter 9. Myoblast-Mediated Gene Transfer for Therapeutic Angiogenesis; Chapter 10. Use of Phage Display to Identify Novel Peptides for Targeted Gene Therapy; Chapter 11. Helper-Dependent Adenoviral VectorsChapter 12. Gene Transfer Methods for Transplantation; Chapter 13. Generation and Growth of Gutted Adenoviral Vectors; Chapter 14. Adenovirus-Mediated Gene Transfer for Cardiovascular and Renal Diseases; Chapter 15. Gene Transfer to Blood Vessels Using Adenoviral Vectors; Chapter 16. Rearrangements in Adenoviral Genomes Mediated by Inverted Repeats; Chapter 17. High-Capacity, Helper-Dependent, "Gutless" AdenoviralVectors for Gene Transfer into Brain; Chapter 18. Gene Therapy Methods in Cardiovascular Diseases; Section III: Adeno-Associated Virus; Chapter 19. Gene Delivery to Cardiac MuscleChapter 20. Recombinant AAV-Mediated Gene Delivery Using Dual Vector Heterodimerization; Chapter 21. Designing and Characterizing Hammerhead Ribozymes for Use in AAV Vector-Mediated Retinal Gene Therapies; Chapter 22. Adeno-Associated Viral Vector-Mediated Gene Therapy of Ischemia-Induced Neuronal Death; Chapter 23. Recombinant Adeno-Associated Viral Vector Production Using Stable Packaging and Producer Cell Lines; Chapter 24. Streamlined Large-Scale Production of Recombinant Adeno-Associated Virus (rAAV) Vectors; Section IV: Lentivirus; Chapter 25. Gene Transfer to the Brain Using Feline Immunodeficiency Virus-Based Lentivirus VectorsChapter 26. Generation of HIV-1 Derived Lentiviral Vectors; Chapter 27. Design, Production, Safety, Evaluation, and Clinical Applications of Nonprimate Lentiviral Vectors; Chapter 28. Gene Transfer to Airway Epithelia Using Feline Immunodeficiency Virus-Based Lentivirus Vectors; Chapter 29. Transduction of a Gene Expression Cassette Using Advanced Generation Lentiviral Vectors; Chapter 30. Construction, Purification, and Characterization of Adenovirus Vectors Expressing Apoptosis- Inducing Transgenes 
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