Handbook of neuroemergency clinical trials /

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During the 1990s, scientific advances in understanding the mechanisms and pathophysiology of acute central nervous system injury were offset by a history of disappointing results from Phase III clinical trials of novel neuroprotective drugs. Numerous novel compounds were tested, and seemingly fell b...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Alves, Wayne M., Skolnick, Brett Evan
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Elsevier Academic Press, �2006.
Temas:
Nervous system > Diseases > Handbooks, manuals, etc.
Neuropharmacology > Handbooks, manuals, etc.
Clinical trials > Handbooks, manuals, etc.
Central Nervous System Diseases > drug therapy
Neuroprotective Agents > therapeutic use
Clinical Trials > methods
Emergency Medicine > methods
Neuropharmacology > methods
Syst�eme nerveux > Maladies > Guides, manuels, etc.
Neuropharmacologie > Guides, manuels, etc.
�Etudes cliniques > Guides, manuels, etc.
HEALTH & FITNESS > Diseases > Nervous System (incl. Brain)
MEDICAL > Neurology.
Clinical trials
Nervous system > Diseases
Neuropharmacology
Handbook
handbooks.
Handbooks and manuals
Handbooks and manuals.
Guides et manuels.
Acceso en línea:Texto completo
Texto completo
Tabla de Contenidos:
  • Acute ischemic stroke / Christopher Bladin and Stephen Davis
  • Subarachnoid hemorrhage / Nader Pouratian, Aaron S. Dumont, and Neal F. Kassell
  • Spontaneous intracerebral hemorrhage / Michael D. Hill
  • Traumatic brain injury / Wayne M. Alves and Lawrence F. Marshall
  • Acute seizures and status epilepticus / Susan Herman
  • Clinical trials in neuro-ophthalmology / Madhura Tamhankar and Laura Balcer
  • Brain resuscitation / Edwin Nemoto and Charles C. King
  • Clinical trials in brain injury after cardiac arrest / Romergryko G. Geocadin and Daniel F. Hanley
  • Efficient dose-response finding strategies for acute neuroemergency treatments / Tom Parke [and others]
  • Biostatistical issues in neuroemergency clinical trials / Wayne M. Alves
  • Data safety and monitoring board: role in acute neurological trials / Brett E. Skolnick
  • Role of a project medical officer in acute neuroemergency clinical trials / Joseph A. Kwentus
  • Ethical considerations in neuroemergency clinical trials / Wayne M. Alves
  • Industry perspective on drug development / Thomas C. Wessel and Christopher Gallen
  • Regulatory perspective / Lisa L. Travis.

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