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Adenosine receptors and Parkinson's disease /

This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. Thi...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Kase, Hiroshi, Richardson, Peter J., Jenner, Peter, 1946-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego, CA : Academic Press, �2000.
Colección:Pure and applied mathematics (Academic Press) ; 60.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Introductory Remarks: Adenosine A2A Receptor Antagonists: A Novel Approach to the Treatment of Parkinson's Disease. / H. Kase
  • Localisation of Adenosine Receptors in Brain and Periphery. / S.J. Augood, P.C. Emsom, and D.G. Standaert
  • Medicinal Chemistry of Adenosine Receptors in Brain and Periphery. / J. Shimada and F. Suzuki
  • Overview of the Physiology and Pharmacology of Adenosine in the Peripheral System. / A. Karasawa
  • Biochemical Characterization of Adenosine Agonists and Antagonists. / H. Nonaka and M. Ichimura
  • Physiology of Adenosine Receptors in the Striatum: Regulation of Striatal Projection Neurons. / A. Mori and T. Shindou
  • The Regulation of Neurotransmitter Release in Basal Ganglia by Adenosine Receptor Agonists and Antagonists in Vitro and in Vivo. / P. Richardson and M. Kurokawa
  • Control of Gene Expression in the Basal Ganglia Induced by Adenosine Receptors. / A. Dixon and P. Richardson
  • Knockout Mice in the Study of Dopaminergic Diseases. / S. Aoyama, J.-H. Baik, H. Kase, and E. Borrelli
  • Effects of Adenosine Receptors Experimental Models of Cognition and Motor Behaviour. / S. Shiozaki, S. Ichikawa, J. Nakamura, and Y. Kuwana
  • Actions of Adenosine Antagonists in a Primate Model of Parkinson's Disease. / T. Kanda and P. Jenner
  • Selective Adenosine A2A Receptor Antagonism as an Alternative Therapy for Parkinson's Disease: A Study in Nonhuman Primates. / A. Tahar, R. Grondin, L. Gregoire, A. Mori, H. Kase, and P.J. Bedard
  • Neurobiology of Adenosine Receptors: Adenosine and its Metabolites in Movement Disorders. / M. Nomoto.