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Adenosine receptors and Parkinson's disease /
This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. Thi...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, CA :
Academic Press,
�2000.
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| Colección: | Pure and applied mathematics (Academic Press) ;
60. |
| Temas: | |
| Acceso en línea: | Texto completo |
| Sumario: | This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. This book covers how the Parkinson's disease antagonist drug, A2A, has been researched, developed, and tested. It is an essential book for researchers interested in the basal ganglia, purine biology, and Parkinson's Disease. Key Features * Discusses the discovery and development of a novel non-dopaminomimetic agent for Parkinson's disease * Provides the first definitive overview of adenosine antagonists and their role in the treatment of Parkinson's disease * Presents a new mechanism of action of adenosine A2A receptor antagonists in motor function Proposes a hypothesis of adenosine A2A receptor function in the striatum * Comprehensive overview of adenosine, its receptor subtypes, their antagonists/agonists from biochemistry, molecular biology, medicinal chemistry, physiology, pharmacology, and neurochemistry viewpoints. |
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| Descripción Física: | 1 online resource (xviii, 275 pages [1] color plate) : illustrations |
| Bibliografía: | Includes bibliographical references and index. |
| ISBN: | 9780124004054 0124004059 9781435605138 1435605136 0080525954 9780080525952 128105383X 9781281053831 9786611053833 6611053832 |