Nonviral vectors for gene therapy /

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Gene transfer within humans has been an obstacle until about 10 years ago. At that time, it was found that viral vectors were effective carriers of "healthy genes" into patients' cells. The problem, however, was that viral vectors proved unnecessarily harmful to humans: subjects exper...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Huang, Leaf, Hung, Mien-chie, Wagner, Ernst, 1960-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego, CA : Academic Press, �1999.
Temas:
Gene therapy.
Genetic vectors.
DNA-ligand interactions.
Liposomes.
Drug targeting.
Genetic Vectors > therapeutic use
Genetic Therapy > methods
Gene Transfer Techniques
Transformation, Genetic
Genetic Therapy
Genetic Vectors
Liposomes
Drug Delivery Systems
Th�erapie g�enique.
Vecteurs de clonage.
Interactions ADN-ligand.
M�edicaments > Ciblage.
HEALTH & FITNESS > Diseases > Genetic.
MEDICAL > Genetics.
DNA-ligand interactions
Drug targeting
Gene therapy
Genetic vectors
gentherapie
gene therapy
genetische vectoren
genetic vectors
gentransfer
gene transfer
moleculaire biologie
molecular biology
medische behandeling
medical treatment
genetische modificatie
genetic engineering
supramoleculaire chemie
supramolecular chemistry
Medicine (General)
Genetic Engineering
Geneeskunde (algemeen)
Genetische modificatie
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Introduction, L. Huang and E. Viroonhatapan.
  • Cationic Liposomes:
  • Progress in Gene Delivery Research and Development, P. Felgner.
  • Cationic Lipid-Mediated Gene Delivery to the Airways, J. Marshall, N. Yew, S. Eastman, C. Jiang, R. Scheule, S. Cheng.
  • Structure and Structure-Activity Relationship of Lipid-Based Gene Delivery Systems, D. Lasic.
  • Self-Assembled Structures of Lipid/DNA Nonviral Gene Delivery Systems from Synchorotron X-Ray Diffraction, C. Safinya, I. Koltover.
  • Sites of Uptake and Expression of Cationic Liposome/DNA Complexes Injected Intravenously, J. McLean, G. Thurston, D. McDonald.
  • Other Vectors:
  • Nuclear Transport of Exogenous DNA, M. Sebesty�en and J. Wolff.
  • Particle-Mediated Gene Delivery: Applications to Canine and Other Larger Animal Systems, N.-S. Yang, G. Hogge, E.G. MacEwen.
  • Polyethylenimines: A Family of Potent Polymers for Nucleic Acid Delivery, A. Kichler, J.-P. Behr, P. Erbacher.
  • Ligand-Polycation Conjugates for Receptor-Targeted Gene Transfer, E. Wagner.
  • The Perplexing Delivery Mechanism of Lipoplexes, L. Barron and F. Szoka, Jr.
  • Biopolymer-DNA Nanospheres, K. Leong.
  • Novel Lipidic Vectors for Gene Transfer, S. Li, L. Huang.
  • Animal Models and Clinical Trials:
  • Mechanisms of Cationic Liposome-Mediated Transfection of the Lung Endothelium, D. Liu, J. Knapp, Y. Song.
  • Cystic Fibrosis Gene Therapy, U. Griesenbach, D. Geddes, E. Alton.
  • Targeting HER-2/neu-Overexpressing Cancer Cells with Transcriptional Repressor Genes Delivered by Cationic Liposome, M.-C. Hung, S.-C. Wang, G. Hortobagyi.
  • Immune Pathways Used in Nucleic Acid Vaccination, G. Rhodes.
  • A Novel Gene Regulatory System, S. Chua, M. Burcin, Y. Wang, S. Tsai.
  • Index.

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