The many faces of RNA /

The Many Faces of RNA is the subject for the eighth SmithKline Beecham Pharmaceuticals Research Symposia. It highlights a rapidly developing area of scientific investigation. The style and format are deliberately designed to promote in-depth presentations and discussions and to facilitate the forgin...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SmithKline Beecham Pharmaceuticals Research Symposia
Otros Autores: Eggleston, D. S. (Drake S.), Prescott, C. D. (Catherine D.), Pearson, N. D. (Neil David), 1962-
Formato: Electrónico Congresos, conferencias eBook
Idioma:Inglés
Publicado: San Diego, CA : Academic Press, �1998.
Temas:
RNA > Congresses.
RNA > Therapeutic use > Congresses.
Ribonucleases > Congresses.
RNA-protein interactions > Congresses.
Antibiotics > Physiological effect > Congresses.
Ribonucleases.
Drugs > Design.
RNA-protein interactions.
RNA > physiology
RNA > therapeutic use
RNA > drug effects
Ribonucleases
RNA-Binding Proteins
Drug Design
ARN > Congr�es.
ARN > Emploi en th�erapeutique > Congr�es.
Ribonucl�eases > Congr�es.
Interactions ARN-prot�eines.
Antibiotiques > Effets physiologiques > Congr�es.
Interactions ARN-prot�eines > Congr�es.
Ribonucl�eases.
Prot�eines de liaison �a l'ARN.
M�edicaments > Conception.
SCIENCE > Life Sciences > Molecular Biology.
Antibiotics > Physiological effect.
RNA.
RNA > Therapeutic use.
rna
Nucleic Acids
Congress
Conference papers and proceedings.
Actes de congr�es.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Introduction.
  • Overview:
  • RNA as a Therapeutic Target for Bleomycin, S.M. Hecht.
  • RNA: Chemistry, Structure and Interactions:
  • Synthetic RNA Modification and Cross-linking Approaches towards the Structure of the Hairpin Ribozyme and the HIV-1 Tat Protein Interaction with TAR RNA, M.J. Gait, D.J. Earnshaw, M.A. Farrow, and N.A. Naryshkin.
  • The Ribosome
  • The Universal Protein-synthesizing Machine, R. Brimacombe.
  • tRNA Recognition by Aminoacyl-tRNA Synthetases, S. Cusack, A. Yaremchuk, and M. Tukalo. RNA-Protein Recognition During RNA Processing and Maturation, G. Varani.
  • RNA as a Target/RNA as a Tool:
  • Exploiting RNA: Potential Targets, Screens and Drug Development, C.D. Prescott, L. Hegg, K. Nurse, R. Gontarek, H. Li, V. Emerick, T. Sterner, M. Gress, G. Thom, S. Guth, and D. Rispoli.
  • Structural Basis for Aminoglycoside Antibiotic Action, J.D. Puglisi.
  • Protein-RNA Recognition in a Highly Conserved Ribosomal Domain Targeted by Thiazole Antibiotics, D.E. Draper.
  • Rnase P and Its Substrate, L.A. Kirsebom.
  • Interfering with Gene Function at the RNA Level with Oligoymes
  • the Development of New Tools and Therapeutics, B.S. Sproat, S.T. George, M. Ma, and A.R. Goldberg.
  • Progress towards Therapeutic Application of SELEX-derived Aptamers, B. Polisky.
  • Catalysis of Organic Reactions by RNA
  • Strategies for the Selection of Catalytic RNAs, A. Jaschke.
  • Conclusions and Opportunities, B.W. Metcalf.
  • Appendix: Abstracts of Posters.
  • Index.

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