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Principles of bone biology /
Principles of Bone Biology is the essential resource for anyone involved in the study of bones. It is the most comprehensive, complete, up-to-date source of information on all aspects of bones and bone biology in one convenient source. Written and published in less than one year, it will become an i...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
�2002.
|
| Edición: | 2nd ed. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- PART I: BASIC PRINCIPLES
- Cell Biology
- The Structure & Development of the Skeleton
- Biomechanics of Bone
- Embryonic Development of Bone and the Molecular Regulation of Intramembranous and Endochondral Bone Formation
- Mesenchymal Stem Cells & Osteoblast Lineage
- Transcriptional Control of Osteoblast Differentiation and Function
- The Osteocyte
- Cells of Bone: Osteoclast Generation
- Osteoclast Function
- Integrin and Calcitonin Receptor Signaling in the Regulation of the Cytoskeleton and Function of Osteoclasts
- Apoptosis in Bone Cells
- Involvement of Nuclear Architecture in Regulating Gene Expression in Bone Cells
- Biochemistry
- Type I Collagen: Structure, Synthesis, and Regulation
- Collagen Crosslinking & Metabolism
- Bone Matrix Proteoglycans & Glycoproteins
- Osteopontin
- Bone Proteinases
- Cell Surface Attachment Molecules
- Intercellular Junctions and Cell-Cell Communication in Bone
- Bone Remodeling and Mineral Homeostasis
- Histomorphometric Analysis of Bone Remodeling
- Phosphorus Homeostasis & Related Disorders
- Magnesium Homeostasis
- Metals in Bone: Aluminum, Boron, Cadmium, Chromium, Lead, Silicon, & Strontium
- The Biology of the Extracellular Ca2+-Sensing Receptor (CaR)
- The Hormones of Bone
- Receptors for Parathyroid Hormone and Parathyroid Hormone-Related Peptide
- Parathyroid Hormone
- Molecular Biology
- Parathyroid Hormone-Receptor Interactions
- Actions of Parathyroid Hormone
- Renal and Skeletal Actions of PTH and PTHrP
- Physiological Actions of PTH and PTHRP: Epidermal, Mammary, Reproductive and Pancreatic Issues
- Vascular, Cardiovascular and Neurological Actions of PTHrP
- Nuclear Receptor Structure (VDR) and Ligand Specificities for Genomic and Rapid Biological Responses
- Vitamin D Gene Regulation
- Photobiology and Non-Calcemic Actions of Vitamin D
- The Structure and Molecular Biology of the Calcitonin Receptor
- Physiology & Pathophysiology of Calcitonin
- Amylin & CGRP
- Other Systemic Hormones That Influence Bone Metabolism
- Estrogens & Progestins
- Selective Estrogen Receptor Modulators (SERMs)
- Mechanisms of Estrogen Action in Bone
- Thyroid Hormone & Bone
- Clinical and Basic Aspects of Glucocorticoid Action in Bone
- Effects of Diabetes & Insulin on Bone Physiology
- Androgens: Receptor Expression and Steroid Action in Bone
- Kinins & Neuro-Osteogenic Factors
- Local Regulators
- The Role of Insulin-like Growth Factors & Binding Proteins in Bone Cell Biology
- Platelet-Derived Growth Factor & the Skeleton
- Fibroblast Growth Factor and Fibroblast Growth Factor Receptor Families in Bone
- Vascular Endothelial Growth Factors
- Transforming Growth Factor (beta)
- Bone Morphogenetic Proteins
- Bone Morphogenetic Protein Receptors & Actions
- Colony-Stimulating Factors
- Local Regulators of Bone: IL-1, TNF, Lymphotoxin, Interferon-?, IL-8, IL-10, IL-4, the LIF/IL-6 Family, and Additional Cytokines
- Prostaglandins & Bone Metabolism
- Nitric Oxide and other Vasoactive Agents
- PART II: MOLECULAR MECHANISMS OF METABOLIC BONE DISEASES
- Molecular Basis of PTH Overexpression
- Familial Benign Hypocalciuric Hypercalcemia and Neonatal Primary Hyperparathyroidism
- Multiple Endocrine Neoplasia Type I
- The Role of the RET Proto-oncogene in Multiple Endocrine Neoplasia Type 2
- Systemic Factors in Skeletal Manifestations of Malignancy
- Local Factors in Skeletal Malignancy
- Molecular Basis of PTH Underexpression
- Jansen's Metaphyseal Chondrodysplasia & Blomstrand's Lethal Chondrodysplasia: Two Genetic Disorders Caused by PTH/PTHrP Receptor Mutations
- Signal Transduction via G Proteins; Pseudohypoparathyroidism
- Other Skeletal Diseases Resulting from G Protein Defects
- Fibrous Dysplasia & McCune-Albright Syndrome
- Osteogenesis Imperfecta
- Hereditary Deficiencies in Vitamin D Action.
- Oncogenic Osteomalacia
- Osteopetrosis
- Hypophosphatasia: Nature's Window on Alkaline Phosphatase Function in Man
- Paget's Disease of Bone
- Genetic Determinants of Bone Mass
- Pathophysiology of Osteoporosis
- Evaluation of Risk for Osteoporosis Fractures
- PART III: PHARMACOLOGIC MECHANISMS OF THERAPEUTICS
- Pharmacologic Mechanisms of Therapeutics: Parathyroid Hormone
- Calcium
- Calcium Receptors as Novel Drug Targets
- Bisphosphonates: Mechanisms of Action
- Fluoride in Osteoporosis
- The Pharmacology of Estrogens in Osteoporosis
- Pharmacologic Mechanisms of Therapeutics: Vitamin D & Analogs
- Molecular and Clinical Pharmacology of Calcitonin
- Growth Hormone and Insulin-like Growth Factor-I Treatment for Metabolic Bone Diseases
- Anabolic Steroid Effects on Bone in Women
- Estrogen Effects on Bone in the Male Skeleton
- Mechanisms of Exercise Effects on Bone
- PART IV: METHODS IN BONE RESEARCH
- Application of Transgenic Mice to Problems of Skeletal Bone
- Use of Cultured Osteoblastic Cells to Identify and Characterize Transcriptional Regulatory Complexes
- Current Methodologic Issues in Cell & Tissue Culture
- Biochemical Markers of Bone Metabolism
- Methods and Clinical Issues in Bone Densitometry and Quantitative Ultrasonometry
- Controversies in Bone Mass Measurement
- Macro and Micro Imaging of Bone Architecture
- Transilial Bone Biopsy
- Animal Models in Osteoporosis Research
- Defining the Genetics of Osteoporosis
- Using the Mouse to Understand Man.
- v. 1
- Part. I. Basic principles
- V. 2
- Part. II. Molecular mechanisims of metabolic bone diseases
- Part. III. Pharmacological mechanisms of therapeutics
- Part. IV. Methods in bone research.