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Molecular biology of B cells /
Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes. The molec...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; Boston :
Elsevier,
2004.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 084 | |a WF 9880 |2 rvk | ||
| 245 | 0 | 0 | |a Molecular biology of B cells / |c edited by Tasuku Honjo, Frederick W. Alt, Michael S. Neuberger. |
| 260 | |a Amsterdam ; |a Boston : |b Elsevier, |c 2004. | ||
| 300 | |a 1 online resource (xiv, 589 pages) : |b color illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 520 | |a Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes. The molecular basis of many diseases due to B cell abnormality is also discussed. This definitive reference is directed at research level immunologists, molecular biologists and geneticists. | ||
| 505 | 0 | |a ORGANIZATION, REARRANGEMENT AND TRANSCRIPTION OF IMMUNOGLOBULIN GENES -- Human Immunoglobulin heavy chains locus -- Immunoglobulin heavy chain genes of mouse -- Immunoglobulin? genes of human and mouse -- Immunoglobulin lambdav (IGL) genes of human and mouse -- The Mechanism of V(D) J Recombination -- Transcription of Immunoglobulin genes -- B CELLS AND THEIR DEVELOPMENT -- Early B cell development to a mature, antigen-sensitive cell -- cellular stages and molecular decisions -- Allelic exclusion, Isotypic exclusion and the Developmental Regulation of V(D)J Recombination -- The Development of Human B Lymphocytes -- Development and function of B cell subsets -- B CELL DIFFERENTIATION INDUCED BY Ag STIMULATION -- Structure and function of B cells antigen receptor complexes -- Regulation of antigen receptor signaling by the co-receptors, CD19 and CD22 -- The dynamic structure of antibody responses -- Dynamics of B cell migration to and within secondary lymphoid organs -- Characteristics of mucosal B cells with emphasis on the human secretory immune system -- The Cellular Basis of B Cell Memory -- Immunoglobulin assembly and secretion -- Fc And Complement Receptors -- Ig GENE ALTERATION IN PERIPHERY -- Regulation of Class Switch Recombination -- Molecular Mechanism of Class Switch Recombination -- Molecular Mechanism of Hypermutation -- Selection During Antigen-Driven B Cell Immune Responses: The Basis for High Affinity Antibody -- DISEASES OF B CELLS -- Chromosomal Translocations in B-cell Leukemias and Lymphomas -- Classification and Characteristics of Mouse B Cell-Lineage Lymphomas -- B cells producing pathogenic autoantibodies -- Immunodeficiencies Caused by B Cell Defects -- EVOLUTION OF Ig GENES -- Diverse forms of Immunoglobulin Genes in Lower Vertebrates -- Immunoglobulin Genes and Generation of Antibody Repertoires in Higher Vertebrates: A Key Role for GALT -- The zebrafish immune system -- The Origin of V(D)J Diversification -- FUNCTION AND APPLICATION OF IMMUNOGLOBULINS -- Antibody Structure and Recognition of Antigen -- Monoclonal antibodies from display libraries -- Humanization of Monoclonal Antibodies -- Human monoclonal antibodies from translocus mice. | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 650 | 0 | |a Molecular immunology. | |
| 650 | 0 | |a B cells. | |
| 650 | 0 | |a Immunoglobulins. | |
| 650 | 0 | |a Immunoglobulin genes. | |
| 650 | 1 | 2 | |a B-Lymphocytes |x immunology |0 (DNLM)D001402Q000276 |
| 650 | 2 | |a B-Lymphocytes |0 (DNLM)D001402 | |
| 650 | 2 | 2 | |a Genes, Immunoglobulin |0 (DNLM)D005803 |
| 650 | 2 | 2 | |a Genetic Phenomena |0 (DNLM)D055614 |
| 650 | 6 | |a Immunologie mol�eculaire. |0 (CaQQLa)201-0203813 | |
| 650 | 6 | |a Lymphocytes B. |0 (CaQQLa)201-0056955 | |
| 650 | 6 | |a Immunoglobulines. |0 (CaQQLa)201-0008346 | |
| 650 | 6 | |a G�enes de l'immunoglobuline. |0 (CaQQLa)201-0276999 | |
| 650 | 7 | |a B cells. |2 fast |0 (OCoLC)fst00824789 | |
| 650 | 7 | |a Immunoglobulin genes. |2 fast |0 (OCoLC)fst00967959 | |
| 650 | 7 | |a Immunoglobulins. |2 fast |0 (OCoLC)fst00967961 | |
| 650 | 7 | |a Molecular immunology. |2 fast |0 (OCoLC)fst01024811 | |
| 650 | 7 | |a B-Lymphozyt |2 gnd |0 (DE-588)4137121-5 | |
| 650 | 7 | |a Molekularbiologie |2 gnd |0 (DE-588)4039983-7 | |
| 650 | 7 | |a Linf�ocitos b. |2 larpcal | |
| 650 | 7 | |a Imunologia celular. |2 larpcal | |
| 650 | 7 | |a Imunoglobulinas. |2 larpcal | |
| 650 | 7 | |a Biologia molecular. |2 larpcal | |
| 655 | 4 | |a Internet Resources. | |
| 655 | 4 | |a Illustrations. | |
| 700 | 1 | |a Honjo, T. |q (Tasuku), |d 1942- | |
| 700 | 1 | |a Alt, Frederick W. | |
| 700 | 1 | |a Neuberger, M. S. |q (Michael S.) | |
| 776 | 0 | 8 | |i Print version: |t Molecular biology of B cells. |d Amsterdam ; Boston : Elsevier, 2004 |z 0120536412 |z 9780120536412 |w (DLC) 2003064380 |w (OCoLC)53970703 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780120536412 |z Texto completo |