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Advances in Antiviral Drug Design.

Regularly reviewing the "state-of-the-art" developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds. It discusses their structure-activity relationship, mechanism and targets of action, pharmacologic...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Elsevier Science Ltd., 2007.
Temas:
Acceso en línea:Texto completo
Texto completo
Tabla de Contenidos:
  • Status presens of antiviral drugs and strategies, Part I: DNA viruses and retroviruses
  • Status presens of antiviral drugs and strategies, Part II: RNA viruses (except retroviruses)
  • Methylenecyclopropane analogues of nucleosides as anti-herpes agents
  • Synthesis and antiviral evaluation of broad spectrum orally active analogs of cidofovir and other acyclic nucleoside phosphonates
  • CCR5 antagonists for the treatment of HIV infection and AIDS
  • The medicinal chemistry of the DATA and DAPY series of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs).