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Medical applications of liposomes /

The development of liposomes as a drug delivery system has fluctuated since its introduction in the late 1960's by A.D. Bangham. While academic research of liposomes as a model membrane system has always flourished, as the exponential growth of papers can testify, the application of these findi...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Lasic, D. D., Papahadjopoulos, Demetrios
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; New York : Elsevier, 1998.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Medical applications of liposomes /  |c edited by D.D. Lasic, D. Papahadjopoulos. 
246 3 0 |a Liposomes 
260 |a Amsterdam ;  |a New York :  |b Elsevier,  |c 1998. 
300 |a 1 online resource (xiv, 779 pages) :  |b illustrations (some color) 
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520 |a The development of liposomes as a drug delivery system has fluctuated since its introduction in the late 1960's by A.D. Bangham. While academic research of liposomes as a model membrane system has always flourished, as the exponential growth of papers can testify, the application of these findings to medically useful products has gone through several crises. Following the original optimism in the 70's and early 80's, a period of severe skepticism ensued at the end of the 80's and beginning of the 90's, culminating in a moderate but real optimism in the mid 90's, as a result of a successful launch of the first products in the US and Europe. In this collection of papers, the editors have gathered the most promising ideas, approaches, applications and commercial developments, thereby presenting an up-to-date compilation of the present status of the field. This includes such broad areas as anti-cancer chemotherapy immune stimulation and infectious diseases. Currently, the major areas of progress are in delivery of anti-fungal agents by conventional liposomes or lipid-based carriers and systemic anticancer therapy using long-circulating liposomes. The future applications as characterized by the direction of present day research is in specific targeting and delivery of informational molecules such as DNA plasmids (genes), antisense oligonucleotides or ribozymes. Other future developments may be in topical delivery, vaccination and in diagnostics. Features of this book: & bull; Contributions from almost all the leading labs in the field & bull; Up-to-date, critical reviews bridged by editors' introductions & bull; Organized into a logical framework. 
505 0 |a 1. Liposomes in Medicine. 2. Stimulation of Immune Response and Vaccination. 3. Infectious Diseases. 4. Cancer Therapy. 5. Gene Therapy. 6. Other Applications. 7. Industrial Manufacturing and Pre-Clinical Testing. 8. Clinical Testing of Liposome Pharmaceuticals. 9. Future Prospects. List of Contributors. Subject Index. 
504 |a Includes bibliographical references and index. 
505 0 |a Sect. I. Liposomes in medicine-- Sect. II. Stimulation of immune response and vaccination-- Sect. III. Infectious diseases-- Sect. IV. Cancer therapy-- Sect. V. Gene therapy-- Sect. VI. Other applications-- Sect. VII. Industrial manufacturing and pre-clinical testing-- Sect. VIII. Clinical testing of liposome pharmaceuticals-- Sect. IX. Future prospects. 
588 0 |a Print version record. 
650 0 |a Liposomes  |x Therapeutic use. 
650 0 |a Drug carriers. 
650 0 |a Drug targeting. 
650 0 |a Gene therapy. 
650 0 |a Vaccination. 
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650 2 2 |a Drug Delivery Systems  |0 (DNLM)D016503 
650 2 2 |a Genetic Therapy  |0 (DNLM)D015316 
650 2 2 |a Neoplasms  |x drug therapy  |0 (DNLM)D009369Q000188 
650 2 2 |a Vaccination  |0 (DNLM)D014611 
650 6 |a Liposomes  |0 (CaQQLa)201-0009732  |x Emploi en th�erapeutique.  |0 (CaQQLa)201-0373975 
650 6 |a M�edicaments  |x Ciblage.  |0 (CaQQLa)201-0196695 
650 6 |a Th�erapie g�enique.  |0 (CaQQLa)201-0193146 
650 6 |a Vaccination.  |0 (CaQQLa)201-0072882 
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650 7 |a Liposomes  |x usage th�erapeutique.  |2 fmesh 
650 7 |a Syst�emes de d�elivrance de m�edicaments.  |2 fmesh 
650 7 |a Tumeurs  |x Traitement m�edicamenteux.  |2 fmesh 
650 7 |a Th�erapie g�enique.  |2 fmesh 
650 7 |a Essais cliniques comme sujet.  |2 fmesh 
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700 1 |a Lasic, D. D. 
700 1 |a Papahadjopoulos, Demetrios. 
776 0 8 |i Print version:  |t Medical applications of liposomes.  |d Amsterdam ; New York : Elsevier, 1998  |z 0444829172  |z 9780444829177  |w (DLC) 98022644  |w (OCoLC)39051854 
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