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|a 173807094
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|a 9780444503312
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|a 0444503315
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|a 616.99/4079
|2 22
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245 |
0 |
0 |
|a Cancer and autoimmunity /
|c editors, Yehuda Shoenfeld, M. Eric Gershwin.
|
250 |
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|a 1st ed.
|
260 |
|
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|a Amsterdam ;
|a New York :
|b Elsevier,
|c �2000.
|
300 |
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|a 1 online resource (xix, 446 pages) :
|b illustrations
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
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|a online resource
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|a Autoantibody library
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|a Of the two disciplines in parallel development for two decades, tumor immunology and transplantation immunology, the latter has thrived and has led to some of the most critical discoveries in immunobiology. The former continues to thwart both scientists and clinicians alike. The goal of immunologists in modern day research is to develop a simple and effective means to manipulate cancer <IT>in vivo, </IT> possibly encompassing several venues: identifying a phenotypic marker and the use of either active or passive immunization; include the use of passive reagents carrying "warheads" to selectively destroy cancer cells; or altering the basic process of cell survival. This excellent multidiscipline-authored volume presents a theme which has not been well described before. The papers include both basic and clinical science and range from sophisticated molecular biology to little more than phenomenology (e.g. the increased association of cancer in some autoimmune diseases and increased presentation of autoimmune phenomena in malignant condition). This, however, is state-of-the-art. This collection of themes will be of use not only to bench scientists, but also to clinicians who treat patients. The book represents progress at the cutting edge of this discipline, and points the way to further developments in the "black box" of immunology
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504 |
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|a Includes bibliographical references and index.
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588 |
0 |
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|a Print version record.
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505 |
0 |
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|a Front Cover -- Cancer and Autoimmunity -- Copyright Page -- Contents -- Preface -- List of Contributors -- Introduction: The Immune System, the Auoimmune State and Autoimmune Disease -- Part I: Malignancies in Autoimmune Diseases -- Chapter 1. Rheumatoid Arthritis and Cancer -- Chapter 2. SLE and Cancer -- Chapter 3. Malignancies Occurring in Scleroderma -- Chapter 4. PSS (Scleroderma) and Cancer -- Chapter 5. Vasculitis and Malignancy -- Chapter 6. Sj�ogren's Syndrome and Lymphoproliferative Disease -- Chapter 7. Polymyalgia Rheumatica, Temporal Arteritis and Occurrence of Malignant Tumors.
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505 |
8 |
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|a Chapter 8. Myositis and Neoplasia -- Chapter 9. Antiphospholipid Antibodies and Malignancies -- Chapter 10. Malignancy in Coeliac Disease and Dermatitis Herpetiformis -- Chapter 11. Autoimmune Rheumatic Diseases and Cancer: Evidence of Causality? -- Part II: Autoimmunity in Malignant States -- Chapter 12. Paraneoplastic Syndromes -- Chapter 13. Paraneoplastic Arthritis -- Chapter 14. Autoantibodies, Autoimmunity and Cancer -- Chapter 15. Antinuclear Antibodies as Potential Markers of Lung Cancer.
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505 |
8 |
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|a Chapter 16. Autoantibodies in Cancer Patients and in Persons with a Higher Risk of Cancer Development -- Chapter 17. Autoantibodies to the Proliferation-Associated Nuclear Protein CENP-F in Cancer -- Chapter 18. p53 Autoantibodies and Cancer: Specificity, Diagnosis and Monitoring -- Chapter 19. Humoral Immune Response Against the Growth Suppressor p53 in Human Malignancies -- Chapter 20. Expression of ETS Family of Genes in Systemic Lupus Erythematosis -- Chapter 21. Immune Response to Tumor Stress Proteins-Implications for Vaccine Development Against Cancer.
|
505 |
8 |
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|a Chapter 22. Autoimmunity and B-Cell Malignancies -- Chapter 23. Autoimmunity in B-Lymphoproliferative Disorders -- Chapter 24. CD5 Positive B Cells: Crossroads of Autoimmunity and Lymphoid Malignancy -- Chapter 25. Thymoma and Autoimmune Diseases -- Chapter 26. Castleman's Disease and Autoimmunity -- Part III: Mechanisms in Cancer and Autoimmunity -- Chapter 27. IgA and Cancer -- Chapter 28. Apoptosis: The Relation Between Anti-Fas Antibodies, and Immunosurveillance Against Cancer and Autoimmunity -- Chapter 29. Hepatitis C Virus, Autoimmunity and Cancer.
|
505 |
8 |
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|a Chapter 30. The Human Neurotropic Virus, JCV, and Its Association with CNS Tumors -- Chapter 31. The Smoking Cancer-Autoimmunity Connection -- Chapter 32. Significance and Regulation of the Expression of MHC Class II Molecules on Autoimmune and Neoplastic Thyroid Cells -- Chapter 33. Cancer Immunity: A Problem of Self-Tolerance -- Chapter 34. Maternal Immune Response to Trophoblast, GTD, and Cancer -- Part IV: Therapy in Autoimmunity and Cancer-Common and Different Denominators -- Chapter 35. Therapy of Cancer and Autoimmunity: Immuno-modulatory Strategies Based on Modified Dendritic Cells.
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546 |
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|a English.
|
650 |
|
0 |
|a Tumors
|x Immunological aspects.
|
650 |
|
0 |
|a Autoimmunity.
|
650 |
|
0 |
|a Autoantibodies.
|
650 |
1 |
2 |
|a Neoplasms
|x immunology
|0 (DNLM)D009369Q000276
|
650 |
2 |
2 |
|a Autoantibodies
|0 (DNLM)D001323
|
650 |
2 |
2 |
|a Autoimmunity
|0 (DNLM)D015551
|
650 |
|
6 |
|a Tumeurs
|x Immunologie.
|0 (CaQQLa)201-0049657
|
650 |
|
6 |
|a Auto-immunit�e.
|0 (CaQQLa)201-0060759
|
650 |
|
6 |
|a Autoanticorps.
|0 (CaQQLa)201-0060758
|
650 |
|
7 |
|a MEDICAL
|x Oncology.
|2 bisacsh
|
650 |
|
7 |
|a HEALTH & FITNESS
|x Diseases
|x Cancer.
|2 bisacsh
|
650 |
|
7 |
|a Autoantibodies
|2 fast
|0 (OCoLC)fst00822532
|
650 |
|
7 |
|a Autoimmunity
|2 fast
|0 (OCoLC)fst00822674
|
650 |
|
7 |
|a Tumors
|x Immunological aspects
|2 fast
|0 (OCoLC)fst01158775
|
650 |
1 |
7 |
|a Kanker.
|2 gtt
|
650 |
1 |
7 |
|a Auto-immuunziekten.
|2 gtt
|
700 |
1 |
|
|a Shoenfeld, Yehuda,
|d 1948-
|
700 |
1 |
|
|a Gershwin, M. Eric,
|d 1946-
|
776 |
0 |
8 |
|i Print version:
|t Cancer and autoimmunity.
|b 1st ed.
|d Amsterdam ; New York : Elsevier, �2000
|z 0444503315
|z 9780444503312
|w (DLC) 99037344
|w (OCoLC)41886153
|
830 |
|
0 |
|a Autoantibody library.
|
856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780444503312
|z Texto completo
|