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Trends in drug research II : proceedings of the 11th Noordwijkerhout-Camerino Symposium, 11-15 May 1997, Noordwijkerhout /

This volume of Pharmacochemistry Library comprises the text of invited lectures presented at the 11th Noordwijkerhout-Camerino Symposium <IT>Trends in Drug Research</IT>, held in Noordwijkerhout, The Netherlands, from 11-15 May 1997. In the programme attention has been given to the gener...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: Noordwijkerhout-Camerino Symposium Noordwijkerhout, Netherlands
Otros Autores: Goot, H. van der
Formato: Electrónico Congresos, conferencias eBook
Idioma:Inglés
Publicado: Amsterdam ; New York : Elsevier, 1998.
Colección:Pharmacochemistry library ; v. 29.
Temas:
Acceso en línea:Texto completo
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Tabla de Contenidos:
  • Selected papers: Preface. Insights into the structure and function of genetic disease genes from genome research and clues for drug therapy (P.L. Pearson). New Developments in synthetic medicinal chemistry (F. Gaultieri). New biocatalytic approaches for the synthesis of chiral drugs, intermediates, and substrates (K. Laumen <IT>et al</IT>.). Ligands for the 5-HT <INF>2C</INF> receptor as potential antidepressents and anxiolytics (D. Leysen, J. Kelder). 5-HT <INF>1A</INF>-affinity, activity and selectivity <IT>versus</IT> D<INF>2</INF>-receptors of flesinoxan and analogous (W. Kuipers). Pharmacokinetics and metabolism in drug development: current and future strategies (D.D. Breimer). Novel approaches towards anti-HIV chemotherapy (E. De Clercq). HBY 097
  • a second-generation nonnucleoside inhibitor of the HIV-1 reverse transcriptase (J-P. Kleim). The HIV tat-TAR interaction, a novel target for drug discovery (J. Karn <IT>et al</IT>.). Diverse approaches to combinatorial library design (E.J. Martin <IT>et al</IT>.). Heterocyclic mixture- based combinatorial libraries: synthesis and analysis of composition (J.S. Kiely, Y. Pei). Chemistry and SAR of prokinetic motilides: non peptidic motilin receptor agonists (P.A. Lartey). Modulators of 5-HT functions in the treatment of gastrointestinal disorders (F.D. King <IT>et al</IT>.). The impact of robotics and novel assay technologies on lead discovery processes (J.G. Houston). Hot topics (P. Angeli). Inverse agonism at G protein-coupled receptors. Studies with wild type and mutated adrenergic and opioid receptors (G. Milligan). Antibiotic resistance
  • a view from the pharmaceutical industry (R. Bax).