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Handbook of molecular-genetic techniques for brain and behavior research /
The book gives a broad overview of recombinant DNA techniques for the behavioral neuroscientist, with illustrative examples of applications. Species covered include rodents (mainly mice), <IT>Drosophila melanogaster, Caenorhabditis elegans</IT> and <IT>Danio rerio.</IT> Exper...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; New York :
Elsevier,
1999.
|
| Edición: | 1st ed. |
| Colección: | Techniques in the behavioral and neural sciences ;
v. 13. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo Texto completo |
MARC
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| 245 | 0 | 0 | |a Handbook of molecular-genetic techniques for brain and behavior research / |c editors, W.E. Crusio and R.T. Gerlai. |
| 250 | |a 1st ed. | ||
| 260 | |a Amsterdam ; |a New York : |b Elsevier, |c 1999. | ||
| 300 | |a 1 online resource (xxvii, 965 pages) : |b illustrations (some color) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Techniques in the behavioral and neural sciences ; |v v. 13 | |
| 520 | |a The book gives a broad overview of recombinant DNA techniques for the behavioral neuroscientist, with illustrative examples of applications. Species covered include rodents (mainly mice), <IT>Drosophila melanogaster, Caenorhabditis elegans</IT> and <IT>Danio rerio.</IT> Experimental techniques required to characterize the behavioral phenotypes of mutant animals is provided. Several aspects of novel molecular-genetic techniques are overviewed and possible research strategies are explained. The sections of the book start with general descriptions of techniques followed by illustrative examples. It is divided into six sections. Section 1, bioinformatics and genomics research. Section 2, top-down strategies, where the researcher starts with the phenotype and then analyzes the associated genes; bottom-up strategies, where the physiological chain leading to a phenotype is analyzed starting from the gene product. Section 3, transgenic approaches in rodents including overexpressing foreign genes and gene-targeting; systemic manipulation approaches directly targeting the central nervous system and methods used with invertebrates. Section 4, methods used to evaluate relevant behavioral phenotypes, including learning and aggression. Section 5, examples on molecular brain research in man. Section 6, ethical aspects of research in this field. | ||
| 505 | 0 | |a Ch. 1. Neurobehavioral informatics and statistics -- Ch. 2. Searching for new genes -- Ch. 3. Manipulating known genes -- Ch. 4. Evaluating behavioral phenotypes in rodents -- Ch. 5. Human neurobehavioral disorders: from molecular genetics to genetic animal modes -- Ch. 6. Ethical considerations. | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 506 | |3 Use copy |f Restrictions unspecified |2 star |5 MiAaHDL | ||
| 533 | |a Electronic reproduction. |b [Place of publication not identified] : |c HathiTrust Digital Library, |d 2010. |5 MiAaHDL | ||
| 538 | |a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. |u http://purl.oclc.org/DLF/benchrepro0212 |5 MiAaHDL | ||
| 583 | 1 | |a digitized |c 2010 |h HathiTrust Digital Library |l committed to preserve |2 pda |5 MiAaHDL | |
| 650 | 0 | |a Neurogenetics |v Handbooks, manuals, etc. | |
| 650 | 0 | |a Neuropsychology |v Handbooks, manuals, etc. | |
| 650 | 0 | |a Genetic psychology |v Handbooks, manuals, etc. | |
| 650 | 0 | |a Neuropsychology. | |
| 650 | 1 | 2 | |a Nervous System Diseases |x genetics |0 (DNLM)D009422Q000235 |
| 650 | 2 | 2 | |a Molecular Biology |0 (DNLM)D008967 |
| 650 | 2 | 2 | |a Neuropsychology |0 (DNLM)D009484 |
| 650 | 6 | |a Neurog�en�etique |0 (CaQQLa)201-0102990 |v Guides, manuels, etc. |0 (CaQQLa)201-0377046 | |
| 650 | 6 | |a Psychologie g�en�etique |0 (CaQQLa)201-0066386 |v Guides, manuels, etc. |0 (CaQQLa)201-0377046 | |
| 650 | 6 | |a Neuropsychologie. |0 (CaQQLa)201-0010136 | |
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| 700 | 1 | |a Crusio, W. E. | |
| 700 | 1 | |a Gerlai, R. T. | |
| 776 | 0 | 8 | |i Print version: |t Handbook of molecular-genetic techniques for brain and behavior research. |b 1st ed. |d Amsterdam ; New York : Elsevier, 1999 |z 0444502394 |z 9780444502391 |w (DLC) 99038172 |w (OCoLC)41712504 |
| 830 | 0 | |a Techniques in the behavioral and neural sciences ; |v v. 13. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780444502391 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/publication?issn=09210709&volume=13 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/09210709/13 |z Texto completo |