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Alkaloids : chemical and biological perspectives /

Acronycine, a potent antitumor agent, was discovered in the bark of the small Australian Rutaceous tree, <IT>Acronychia baueri </IT>Schott. This new work presents a comprehensive survey of the isolation, structure determination, methods of synthesis, and the biological properties of acro...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Pelletier, S. W. (S. William), 1924-2004
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : [Oxford] : Elsevier ; Pergamon, 1998-<>
Edición:1st ed.
Temas:
Acceso en línea:Texto completo
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MARC

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245 0 0 |a Alkaloids :  |b chemical and biological perspectives /  |c edited by S. William Pelletier and Departement of Chemistry, the University of Georgia. 
250 |a 1st ed. 
260 |a Amsterdam :  |b Elsevier ;  |a [Oxford] :  |b Pergamon,  |c 1998-<> 
300 |a 1 online resource (volumes <1-12>) :  |b illustrations 
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520 |a Acronycine, a potent antitumor agent, was discovered in the bark of the small Australian Rutaceous tree, <IT>Acronychia baueri </IT>Schott. This new work presents a comprehensive survey of the isolation, structure determination, methods of synthesis, and the biological properties of acronycine, as well as an account of natural and synthetic analogues of acronycine, and their biological properties. Solanum alkaloids were reviewed in 1990 and this book surveys the new developments (isolation procedures, structural elucidation methods) and critically updates earlier reviews. In addition it presents the interesting chemistry and synthesis of cyclopeptide alkaloids. These cyclopeptide alkaloids have been isolated from ascidians, sea hares, and cyanobacteria. Also included are reviews of the use of the functionalized lactam, pyroglutamic acid, as a chiral template for the synthesis of alkaloids. The second review examines the on-line coupling of capillary electrophoresis (CE) and mass spectrometry (MS) for the analysis of alkaloid mixtures. Finally a review of oxygenated analogs of the alkaloid Marcfortine for their potent antiparasitic activity is included at the end of this work. Each chapter in this volume has been reviewed by at least one expert in the field. Indexes for both subjects and organisms are provided. 
505 0 |a Acronycine-type alkaloids: chemistry and biology (F. Tillequin <IT>et al</IT>.). <IT>Solanum</IT> steroid alkaloids -- an update (H. Ripperger). Synthesis and structure-activity studies of <IT>Lissoclinum</IT> peptide alkaloids (P. Wipf). Pyroglutamate as a chiral template for the synthesis of alkaloids (M.B. Smith). Analysis of alkaloids by capillary electrophoresis and capillary electrophoresis -- electrospray mass spectrometry (J. S&#xFFFD;tckigt <IT>et al</IT>.). Oxidation of anthelmentic marcofortine A, an indole alkaloid (B.H. Lee <IT>et al</IT>.). Subject index. Organism index. 
504 |a Includes bibliographical references and indexes. 
588 0 |a Print version record. 
650 0 |a Alkaloids. 
650 2 |a Alkaloids  |0 (DNLM)D000470 
650 6 |a Alcalo&#xFFFD;ides.  |0 (CaQQLa)201-0001052 
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650 7 |a Alkaloids  |2 fast  |0 (OCoLC)fst00805398 
700 1 |a Pelletier, S. W.  |q (S. William),  |d 1924-2004. 
776 0 8 |i Print version:  |t Alkaloids.  |b 1st ed.  |d Amsterdam : Elsevier ; [Oxford] : Pergamon, 1998-<>  |z 0080428053  |z 9780080428055  |w (OCoLC)42049056 
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