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The Histamine H3 receptor : a target for new drugs /
In the early eighties when the H<INF>3</INF> receptor was identified, many thought that an H<INF>3</INF> ligand, an agonist or an antagonist, would become available as a therapeutic agent. This has not occurred. The reason for this could be the fact that many investigators co...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; New York :
Elsevier,
1998.
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| Edición: | 1st ed. |
| Colección: | Pharmacochemistry library ;
v. 30. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo Texto completo |
Tabla de Contenidos:
- Preface. Subclassification of histamine receptors, H<INF>3</INF>-receptor subtypes? Localization of H<INF>3</INF> receptors in the brain (J.M. Arrang <IT>et al.</IT>). Modulation of <IT>in vitro</IT> neurotransmission in the CNS and in the retina via H<INF>3</INF> heteroreceptors (E. Schlicker, M. Kathmann). H<INF>3</INF> receptor modulation of the release of neurotransmitters <IT>in vivo</IT> (P. Blandina <IT>et al.</IT>). H<INF>3</INF> receptor modulation of neuroendocrine responses to histamine and stress (U. Knigge <IT>et al.</IT>). Functional role of histamine H<INF>3</INF> receptors in peripheral tissues (G. Bertaccini <IT>et al.</IT>). Biochemical properties of the histamine H<INF>3</INF> receptor (M. Hoffman <IT>et al.</IT>). Radioligands for the histamine H<INF>3</INF> receptor and their use in pharmacology (F.P. Jansen <IT>et al.</IT>). Substituted imidazoles, the key to histaminergic receptors (W.M.P.B. Menge, H. Timmerman). Synthesis of radioligands for the histamine H<INF>3</INF> receptor (A.D. Windhorst <IT>et al.</IT>). Medicinal chemistry of histamine H<INF>3</INF> receptor antagonists (J.G. Phillips, S.M. Ali). Molecular modelling studies of histamine H<INF>3</INF> receptor ligands (I.J.P. de Esch <IT>et al.</IT>). Brain histamine in pathophysiological conditions and brain diseases (P. Panula <IT>et al.</IT>). Histamine H<INF>3</INF> antagonists as potential therapeutics in the CNS (K. Onodera, T. Watanabe). Clinical application of HA H<INF>3</INF> receptor antagonists in learning and memory disorders (C.E. Tedford).