HPLC Method Development for Pharmaceuticals.

High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Meth...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Academic Pr, 2007.
Temas:
High performance liquid chromatography > Methodology.
Drugs > Analysis.
Drug development.
Pharmaceutical Preparations > analysis
Chemistry, Pharmaceutical > methods
Chromatography, High Pressure Liquid > methods
Chromatographie en phase liquide �a hautes performances > M�ethodologie.
M�edicaments > Analyse.
M�edicaments > D�eveloppement.
Drug development
Drugs > Analysis
High performance liquid chromatography > Methodology
Acceso en línea:Texto completo
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Tabla de Contenidos:
  • 1. Overview (Satinder Ahuja).
  • 2. HPLC Theory (Y.V. Kazakevich).
  • 3. HPLC Columns and Packings (U.D. Neue <IT>et al</IT>.).
  • 4. Column Characterization and Selection (D. Visky).
  • 5. Chiral Separations (Xiande Wang <IT>et al</IT>.).
  • 6. Contemporary Liquid Chromatographic Systems for Method Development (M. Swartz).
  • 7. Hyphenated Techniques (D.L. Norwood <IT>et al</IT>.).
  • 8. HPLC Sample Preparation (G. Slack, N.H. Snow).
  • 9. Instrument and Software Qualification and Validation (D. Van Geel).
  • 10. Pharmaceutical Development: From Pre-clinical to Post Approval (K. Bynum).
  • 11. HPLC Method Development for Drug Discovery LC-MS Assays in Rapid PK Applications (Xiaoying Xu, W. Korfmacher).
  • 12. HPLC Method Development in Early Phase Pharmaceutical Development (H.T. Rasmussen <IT>et al</IT>.).
  • 13. HPLC Method Development in Late Phase Pharmaceutical Development (M. Ilias Jimidar).
  • 14. Use of HPLC for In-process Testing (C. Richardson).
  • 15. Method Development for Biomolecules (D.E. Raynie, J.L. Driver).
  • 16. Method Validation (M. Ilias Jimidar <IT>et al</IT>.).
  • 17. Troubleshooting HPLC Methods (H. McNair).
  • 18. Molecularly Imprinted Polymers as Sorbents for Separations and Extractions (M.T. Koesdjojo <IT>et al</IT>.).

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