The handbook of metabonomics and metabolomics /

Molecular biology operates at three levels genes, proteins and metabolites. This book is unique in that it provides a comprehensive description of an approach (metabonomics) to characterise the endogenous metabolites in a living system, complementing gene and protein studies (genomics and proteomics...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Lindon, John C., Nicholson, Jeremy K., Holmes, Elaine
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Oxford : Elsevier, 2007.
Edición:1st ed.
Temas:
Molecular biology > Technique > Handbooks, manuals, etc.
Biochemistry > Technique > Handbooks, manuals, etc.
Gene expression > Technique > Handbooks, manuals, etc.
Metabolism.
Molecular genetics.
Biomolecules.
Gene expression.
Molecular Biology > methods
Biochemistry > methods
Gene Expression
Metabolism
Biologie mol�eculaire > Technique > Guides, manuels, etc.
Biochimie > Technique > Guides, manuels, etc.
Expression g�enique > Technique > Guides, manuels, etc.
M�etabolisme.
G�en�etique mol�eculaire.
Biomol�ecules.
Expression g�enique.
metabolism (biological concept)
SCIENCE > Life Sciences > Biochemistry.
Biochemistry > Technique.
Gene expression > Technique.
Molecular biology > Technique.
Chemische Analyse
Metabolit
Metabolom
Nachweis
Handbook
handbooks.
manuals (instructional materials)
Handbooks and manuals.
Guides et manuels.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Chapter 1. Metabonomics and metabolomics techniques and their applications in mammalian systems.
  • Chapter 2. Cellular metabolomics: the quest for pathway structure.
  • Chapter 3. NMR spectroscopy techniques for application to metabonomics.
  • Chapter 4. High-resolution magic angle spinning NMR spectroscopy.
  • Chapter 5. Chromatographic and electrophoretic separations combined with mass spectrometry for metabonomics.
  • Chapter 6. Chemometrics techniques for metabonomics.
  • Chapter 7. Nonlinear chemometric methods for the analysis of metabolic profiles.
  • Chapter 8. Databases and standardisation of reporting methods for metabolic studies.
  • Chapter 9. Metabonomics in preclinical pharmaceutical discovery and development.
  • Chapter 10. Metabolic applications in clinical pharmaceutical R & D.
  • Chapter 11. Exploiting the potential of metabonomics in large population studies: three venues.
  • Chapter 12. Metabolite profiling and cardiovascular disease.
  • Chapter 13. The role of NMR-based metabolomics in cancer.
  • Chapter 14. NMR spectroscopy of body fluids as a metabolomics approach to inborn errors of metabolism.
  • Chapter 15. A survey of metabonomics approaches for disease characterisation.
  • Chapter 16. Metabolic profiling: applications in plant science.
  • Chapter 17. In vivo NMR applications of metabonomics.
  • Chapter 18. Applications of metabonomics within environmental toxicology.
  • Chapter 19. Global systems biology through integration of "omics" results.

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