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Adenoviral vectors for gene therapy /

Adenoviral Vectors for Gene Therapy provides detailed and comprehensive coverage of these important therapeutic agents. The topics covered in this book range from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology and the use...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Curiel, David, Douglas, Joanne T.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Academic Press, �2002.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Adenovirus Structure
  • Biology of Adenovirus Cell Entry
  • Adenovirus Replication
  • Adenoviral Vector Construction I: Mammalian Systems
  • Adenoviral Vector Construction II: Bacterial Systems
  • Propagation of Adenoviral Vectors: Use of PER. C6 Cells
  • Purification of Adenovirus
  • Targeted Adenoviral Vectors I: Transductional Targeting
  • Targeted Adenoviral Vectors II: Transcriptional Targeting
  • Development of Attenuated Replication Competent Adenoviruses ARCAs) for the treatment of Prostate Cancer
  • Replication-Selective Oncolytic Adenovirus EI-Region Mutants: Virotherapy for Cancer
  • Innate Immune Responses to in Vivo Adenovirus Infection
  • Humoral Immune Response
  • Novel Methods to Eliminate the Immune Response to Adenovirus Gene Therapy
  • High-Capacity "Gutless" Adenoviral Vectors: Technical Aspects and Applications
  • Xenogenic Adenoviral Vectors
  • Hybrid Adenoviral Vectors
  • Utility of Adenoviral Vectors in Animal Models of Human Disease I: Cancer
  • Utiltity of Adenoviral Vectors in Animal Models of Human Disease II: Genetic Disease
  • Utility of Adenoviral Vectors in Animal Models of Human Disease III: Acquired Diseases
  • Testing of Adenoviral Vector Gene Transfer Products: FDA Expectations
  • Imaging Adenovirus-Medicated Gene Transfer.