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Viral vectors : gene therapy and neuroscience applications /

Genetic manipulation of the adult mammalian nervous system is one of the most exciting areas in contemporary neurobiology. The explosive growth of this field has been facilitated by harnessing the power of viruses to transfer genetic material into mammalian cells. Viral Vectors: Gene Therapy and Neu...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Kaplitt, Michael G., Loewy, Arthur D.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press, �1995.
Temas:
Acceso en línea:Texto completo

MARC

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020 |a 9780080543574  |q (electronic bk.) 
020 |a 008054357X  |q (electronic bk.) 
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035 |a (OCoLC)162129243  |z (OCoLC)174131344  |z (OCoLC)176889257  |z (OCoLC)180752433  |z (OCoLC)647656219  |z (OCoLC)989397143  |z (OCoLC)1035660527 
050 4 |a RC361  |b .V55 1995eb 
060 4 |a 1995 I-901 
060 4 |a QH 442.2  |b V813 1995 
072 7 |a HEA  |x 039110  |2 bisacsh 
072 7 |a MED  |x 056000  |2 bisacsh 
082 0 4 |a 616.8  |2 22 
245 0 0 |a Viral vectors :  |b gene therapy and neuroscience applications /  |c edited by Michael G. Kaplitt, Arthur D. Loewy. 
260 |a San Diego :  |b Academic Press,  |c �1995. 
300 |a 1 online resource (xxvii, 486 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
520 |a Genetic manipulation of the adult mammalian nervous system is one of the most exciting areas in contemporary neurobiology. The explosive growth of this field has been facilitated by harnessing the power of viruses to transfer genetic material into mammalian cells. Viral Vectors: Gene Therapy and Neuroscience Applications represents the first comprehensive review of viral vector applications to the nervous system by leaders in virology, molecular neurobiology, neuroanatomy, and developmental neurobiology. It serves both as a source of fundamental information for those newly interested in viral vectors and as a compilation of state-of-the-art technologies and applications for more experienced researchers. This work provides expert background information on viral systems, and the broad range of applications will help readers appreciate the current and future impact of viral vectors in both clinical and basic neuroscience. 
505 0 |a Herpes Simplex Virus as a Gene Delivery Vector for the Central Nervous System. Biology of Herpes Simplex Virus (HSV) Defective Viruses and Development of the Amplicon System. Group C Adenoviruses as Vectors for Gene Therapy. Genetics and Biology of Adeno-Associated Virus. Genetics and Biology of Retroviral Vectors. HSV Vectors in the Mammalian Brain: Molecular Analysis of Neuronal Physiology, Generation of Genetic Models, And Gene Therapy of Neurological Disorders. The Use of Defective Herpes Simplex Virus Amplicon Vectors to Modify Neural Cells and the Nervous System. Viral Vector-Mediated Gene Transfer in the Nervous System: Application to the Reconstruction of Neural Circuits in the Injured Mammalian Brain. The Use of Herpes Simplex Virus Vectors for Protection from Necrotic Neuron Death. In Vivo Promoter Analysis in the Adult Central Nervous Systems Using Viral Vectors. Adenoviral Mediated Gene Transfer: Potential Therapeutic Applications. Transfer and Expression of Potentially Therapeutic Genes Into the Mammalian Central Nervous System in Vivo Using Adeno-Associated Viral Vectors. Genetic Modification of Cells with Retrovirus Vector for Grafting Into the Central Nervous System. Virus Vector-Mediated Transfer of Drug-Sensitivity Genes for Experimental Brain Tumor Therapy. Brain Tumor Therapy Using Genetically Engineered Replication-Competent Virus. Transfer and Expression of Antioncogenes and Paraneoplastic Genes in Normal and Neoplastic Cells in Vitro and in Vivo. Transneuronal Tracing with Alphaherpesviruses: A Review of the Methodology. Pseudorabies Virus Replication and Assembly in the Rodent Central Nervous System. Pseudorabies Virus Replication and Assembly in the Rodent Central Nervous System. Pseudorabies Virus: A Transneuronal Tracer for Neuroanatomical Studies. Molecular Properties of Alphaherpesviruses Used in Transneuronal Pathway Tracing. Molecular Analysis of Rabies and Pseudorabies Neurotropism. The Use of Retroviral Vectors in the Study of Cell Lineage and Migration During the Development of the Mammalian Central Nervous System. Retroviral Vectors for the Study of Neuroembryology: Immortalization of Neural Cells. References. Index. 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
650 0 |a Central nervous system  |x Diseases  |x Gene therapy. 
650 0 |a Genetic vectors. 
650 0 |a Viruses. 
650 0 |a Gene therapy. 
650 1 2 |a Genetic Vectors  |0 (DNLM)D005822 
650 2 |a Viruses  |0 (DNLM)D014780 
650 2 2 |a Central Nervous System Diseases  |x genetics  |0 (DNLM)D002493Q000235 
650 2 2 |a Central Nervous System Diseases  |x therapy  |0 (DNLM)D002493Q000628 
650 2 2 |a Central Nervous System  |x physiology  |0 (DNLM)D002490Q000502 
650 2 2 |a Genes, Viral  |x genetics  |0 (DNLM)D005814Q000235 
650 2 2 |a Gene Expression Regulation, Viral  |0 (DNLM)D015967 
650 2 2 |a Genetic Therapy  |0 (DNLM)D015316 
650 6 |a Syst�eme nerveux central  |0 (CaQQLa)201-0011353  |x Maladies  |0 (CaQQLa)201-0011353  |x Th�erapie g�enique.  |0 (CaQQLa)201-0380879 
650 6 |a Vecteurs de clonage.  |0 (CaQQLa)201-0024829 
650 6 |a Virus.  |0 (CaQQLa)201-0078047 
650 6 |a Th�erapie g�enique.  |0 (CaQQLa)201-0193146 
650 7 |a HEALTH & FITNESS  |x Diseases  |x Nervous System (incl. Brain)  |2 bisacsh 
650 7 |a MEDICAL  |x Neurology.  |2 bisacsh 
650 7 |a Gene therapy  |2 fast  |0 (OCoLC)fst00939638 
650 7 |a Genetic vectors  |2 fast  |0 (OCoLC)fst00940107 
650 7 |a Viruses  |2 fast  |0 (OCoLC)fst01167771 
653 0 |a Humans  |a Central nervous system  |a Diseases 
700 1 |a Kaplitt, Michael G. 
700 1 |a Loewy, Arthur D. 
776 0 8 |i Print version:  |t Viral vectors.  |d San Diego : Academic Press, �1995  |z 0123975700  |z 9780123975706  |w (DLC) 94049185  |w (OCoLC)31819663 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780123975706  |z Texto completo