High throughput analysis for early drug discovery /

This book offers concise and unbiased presentations by synthetic and analytical chemists who have been involved in creating and moving the field of combinatorial chemistry into the academic and industrial mainstream. Since the synthetic method often dictates the appropriate types of analysis, each c...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Kyranos, James N.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Elsevier, 2004.
Edición:1st ed.
Temas:
High throughput screening (Drug development)
Combinatorial chemistry.
Combinatorial Chemistry Techniques > methods
Drug Evaluation, Preclinical > methods
Pharmaceutical Preparations > analysis
Criblage �a haut d�ebit (D�eveloppement des m�edicaments)
Chimie combinatoire.
MEDICAL > Drug Guides.
MEDICAL > Pharmacology.
MEDICAL > Pharmacy.
MEDICAL > Nursing > Pharmacology.
Combinatorial chemistry
Internet Resources.
Illustrations.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • High Throughput Analysis of Combinatorial Libraries Encoded with Electrophoric Molecular Tags, Adolor Corporation.
  • Analysis of a Combinatorial Library Synthesized Using a Split-and-pool Irori MicroKan Method for Development and Production, Boehringer Ingelheim Pharmaceuticals, Inc.
  • High-Throughput Mass Spectrometry-Flow Injection Analysis, Procter and Gamble Pharmaceuticals.
  • High-Throughput Flow-Injection ESI and APCI Mass Spectrometry for Combinatorial Chemistry: Automated Acquisition and Interpretation for Multi-Sprayer Low-Resolution and FTMS High-Resolution Exact-Mass Measurements, Wyeth Research.
  • Purity and Quantity Determination of Parallel Synthesis Compound Libraries, ArQule, Inc.
  • High-Throughput Parallel LC/MS/ELSD of Combinatorial Libraries Using the Eight-Channel LCT System With MUX Technology, Nereus Pharmaceuticals Inc and University of California, San Diego.
  • Purification and Analysis of Parallel Libraries, Albany Molecular.
  • Screening Single Bead Combinatorial Libraries Using Capillary HPLC and MALDI-TOF-MS, National Research Council.
  • The Role of NMR in the Analysis of Chemical Libraries, Bristol Meyers Squibb.

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