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Phosphodiesterase inhibitors /

Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958. In the decade of the '70s, various PDE isoenzymes were defined which led to the development of the second generation of PDE inhibitors. Currently a variety of thes...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Schudt, Christian, Dent, Gordon, Rabe, Klaus F.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press, 1996.
Colección:Handbook of immunopharmacology. Drugs.
Temas:
Acceso en línea:Texto completo
Descripción
Sumario:Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958. In the decade of the '70s, various PDE isoenzymes were defined which led to the development of the second generation of PDE inhibitors. Currently a variety of these new inhibitors are under test as potential anti-inflammatory drugs. During the past five years, molecular biology has revealed a superfamily of these phosphodiesterase isoenzymes. This book summarizes the present state of knowledge, as well as giving a comprehensive description of the compounds available. It will be invaluable for everyone who wants to choose the most suitable PDE inhibitor for their research or who is dealing with such drugs in a clinical setting. Key Features * Utilizes actual testing and research of new PDE inhibitors * Valuable for researchers and students alike.
Descripción Física:1 online resource (xvi, 228 pages, 2 unnumbered pages of plates) : illustrations (some color)
Bibliografía:Includes bibliographical references and index.
ISBN:9780122107207
0122107209
9780080538815
0080538819
1281058971
9781281058973