In vitro methods in pharmaceutical research /

In Vitro Methods in Pharmaceutical Research provides a comprehensive guide to laboratory techniques for evaluating in vitro organ toxicity using cellular models. Step-by-step practical tips on how to perform and interpret assays for drug metabolism and toxicity assessment are provided, along with a...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Castell, Jos�e V., G�omez-Lech�on, Mar�ia Jos�e
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press, �1997.
Temas:
Drugs > Research.
Pharmacy > Research.
Drugs > Side effects.
Drug-Related Side Effects and Adverse Reactions
Toxicity Tests
Cells, Cultured > drug effects
M�edicaments > Recherche.
M�edicaments > Effets secondaires.
MEDICAL > Pharmacology.
In-vitro-onderzoek.
Farmacie.
Electronic books.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • D.W. Straughan, J.H. Fentem, and M. Balls, Replacement Alternative and Complementary In Vitro Methods in Pharamaceutical Research.
  • M.D. Barratt and M. Chamberlain, Integration of QSAR and In Vitro Toxicology.
  • F.A. Barile, Continuous Cell Lines as a Model for Drug Toxicity Assessment.
  • P. Bach, In Vitro Models for Nephrotoxicity Studies.
  • A.E.M. Vickers, Experimental In Vitro Models to Evaluate Hepatotoxicity.
  • M.J. Gomez-Lechon, T. Donato, X. Ponsoda, R. Fabra, R. Trullenque, and J.V. Castell, Isolation, Culture and Use of Human Hepatocytes in Drug Research.
  • E. McFarlane-Abdulla, and I.C. Campbell, Studies of Nephrotoxicity in Cellular Studies.
  • M. Adolphe, S. Thenet-Gauci, and S. Demignot, Chondrocyte Culture: A Target System to Evaluate Pharmaco-Toxicological Effects of Drugs.
  • E. Chacon, D. Acosta, and J.J. Lemasters, Primary Cultures of Cardiac Myocytes as In Vitro Models for Pharmacological and Toxicological Assessments.
  • R. Roguet, Cutaneous Pharmacotoxicology In Vitro.
  • H. Spielmann, Ocular Irritation.
  • M.A. Miranda, Phototoxicity of Drugs.
  • I. de G. Mitchell and R.D. Combes, In Vitro Genotoxicity and Cell Transformation Assessment.
  • B. Schmid, R. Bechter, and P. Kucera, The Use of Whole Embryo Cultures in In Vitro Teratogenicity Testing.
  • J.V. Castell, M.J. Gomez-Lechon, X. Ponsoda, and R. Bort, In Vitro Investigation of the Molecular Mechanisms of Hepatotoxicity.
  • A. Guillouzo, Biotransformation of Drugs by Hepatocytes.
  • K. Mace, E.A. Offord, and A.M.A. Pfeifer, Drug Metabolism and Carcinogen Activation Studies with Human Genetically Engineered Cells.

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