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Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol-linked proteins /

Paroxysmal Nocturnal Hemoglobinuria (PNH) has been recognized for over a century. This mysterious disease is now understood at the level of the gene and the protein. The pathophysiology is related to a class of cell surface proteins with distinctive biochemical and physical characteristics. Recently...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Young, Neal S., Moss, Joel
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press, �2000.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • A Brief History of PNH
  • Genetics of PNH
  • Hemolysis in PNH
  • Thrombotic Complications in PNH
  • Bone Marrow Failure in PNH
  • Animal Models of PNH
  • The Function of GPI-Anchored Proteins
  • GPI in Lower Animals
  • Synthesis of the GPI Anchor
  • Functional and Structural Organization of GPI-Anchored Proteins in Cellular Membranes
  • Structure and Function of GPI-Specific Phospholipases.