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Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol-linked proteins /
Paroxysmal Nocturnal Hemoglobinuria (PNH) has been recognized for over a century. This mysterious disease is now understood at the level of the gene and the protein. The pathophysiology is related to a class of cell surface proteins with distinctive biochemical and physical characteristics. Recently...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
�2000.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 001 | SCIDIR_ocn162129026 | ||
| 003 | OCoLC | ||
| 005 | 20231117014748.0 | ||
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| 008 | 070802s2000 caua ob 001 0 eng d | ||
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| 020 | |a 9780127729404 | ||
| 020 | |a 0127729402 | ||
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| 035 | |a (OCoLC)162129026 |z (OCoLC)156790643 |z (OCoLC)648303031 |z (OCoLC)823826912 |z (OCoLC)823896301 |z (OCoLC)824088464 |z (OCoLC)824134884 |z (OCoLC)1035656101 |z (OCoLC)1162271304 | ||
| 050 | 4 | |a RC641.7.P37 |b P37 2000eb | |
| 060 | 4 | |a 2000 E-108 | |
| 060 | 4 | |a WJ 344 |b P257 2000 | |
| 072 | 7 | |a MED |x 038000 |2 bisacsh | |
| 072 | 7 | |a MJF |2 bicssc | |
| 082 | 0 | 4 | |a 616.1/51 |2 22 |
| 245 | 0 | 0 | |a Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol-linked proteins / |c edited by Neal S. Young, Joel Moss. |
| 246 | 3 | 0 | |a PNH and the GPI-linked proteins |
| 260 | |a San Diego : |b Academic Press, |c �2000. | ||
| 300 | |a 1 online resource (xiii, 279 pages) : |b illustrations (some color) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 520 | |a Paroxysmal Nocturnal Hemoglobinuria (PNH) has been recognized for over a century. This mysterious disease is now understood at the level of the gene and the protein. The pathophysiology is related to a class of cell surface proteins with distinctive biochemical and physical characteristics. Recently it has been acknowledged that PNH is not rare, and once sensitive assays--based on the chemistry of the proteins--can be applied to many patients. Written by international experts in the field, this book includes a number of distinctive characteristics, such as the clinical features of PNH, the mechanism of hemolysis, the biochemistry of glycosylphosphoinositol anchors, and the chemistry and biophysics of GPI-anchored proteins. This unique and timely volume will have a wide audience, including hematologists and oncologists with a clinical interest in this disease, as well as basic biochemists, immunologists, and cell biologists studying this class of proteins. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a A Brief History of PNH -- Genetics of PNH -- Hemolysis in PNH -- Thrombotic Complications in PNH -- Bone Marrow Failure in PNH -- Animal Models of PNH -- The Function of GPI-Anchored Proteins -- GPI in Lower Animals -- Synthesis of the GPI Anchor -- Functional and Structural Organization of GPI-Anchored Proteins in Cellular Membranes -- Structure and Function of GPI-Specific Phospholipases. | |
| 588 | 0 | |a Print version record. | |
| 546 | |a English. | ||
| 650 | 0 | |a Paroxysmal hemoglobinuria. | |
| 650 | 0 | |a Phosphoinositides. | |
| 650 | 0 | |a Glycoproteins. | |
| 650 | 0 | |a Membrane proteins. | |
| 650 | 0 | |a Cellular signal transduction. | |
| 650 | 1 | 2 | |a Hemoglobinuria, Paroxysmal |0 (DNLM)D006457 |
| 650 | 2 | |a Phosphatidylinositols |0 (DNLM)D010716 | |
| 650 | 2 | |a Membrane Proteins |0 (DNLM)D008565 | |
| 650 | 2 | |a Signal Transduction |0 (DNLM)D015398 | |
| 650 | 2 | 2 | |a Glycoproteins |0 (DNLM)D006023 |
| 650 | 2 | 2 | |a Glycosylphosphatidylinositols |0 (DNLM)D017261 |
| 650 | 6 | |a H�emoglobinurie paroxystique nocturne. |0 (CaQQLa)201-0329296 | |
| 650 | 6 | |a Phospho-inositides. |0 (CaQQLa)201-0179510 | |
| 650 | 6 | |a Prot�eines membranaires. |0 (CaQQLa)201-0033976 | |
| 650 | 6 | |a Transduction du signal cellulaire. |0 (CaQQLa)201-0206812 | |
| 650 | 6 | |a Glycoprot�eines. |0 (CaQQLa)201-0006537 | |
| 650 | 7 | |a MEDICAL |x Hematology. |2 bisacsh | |
| 650 | 7 | |a Cellular signal transduction |2 fast |0 (OCoLC)fst00850288 | |
| 650 | 7 | |a Glycoproteins |2 fast |0 (OCoLC)fst00943791 | |
| 650 | 7 | |a Membrane proteins |2 fast |0 (OCoLC)fst01015850 | |
| 650 | 7 | |a Paroxysmal hemoglobinuria |2 fast |0 (OCoLC)fst01053903 | |
| 650 | 7 | |a Phosphoinositides |2 fast |0 (OCoLC)fst01061408 | |
| 653 | 0 | 0 | |a hemoglobinurie |
| 653 | 0 | 0 | |a haemoglobinuria |
| 653 | 1 | 0 | |a Human Pathology |
| 653 | 1 | 0 | |a Humane pathologie |
| 655 | 4 | |a Internet Resources. | |
| 700 | 1 | |a Young, Neal S. | |
| 700 | 1 | |a Moss, Joel. | |
| 776 | 0 | 8 | |i Print version: |t Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol-linked proteins. |d San Diego : Academic Press, �2000 |z 0127729402 |z 9780127729404 |w (DLC) 99065876 |w (OCoLC)43913628 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780127729404 |z Texto completo |