Platelet protocols : research and clinical laboratory procedures /
Platelets are fragments of blood cells that occur in the blood of vertebrates and are associated with blood clotting. Scientists have made great strides in recent years in understanding what stimulates platelets to form blood clots at the molecular level and in developing drugs to inhibit platelet a...
Clasificación: | Libro Electrónico |
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Autor principal: | |
Otros Autores: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
San Diego :
Academic Press,
�1999.
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Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Basic Introduction to Platelets:
- Introduction.
- Platelets in Hemostasis.
- Membrane Surface Proteins.
- Events Associated with Platelet Aggregation.
- Agonists.
- Coagulation.
- Laboratory Evaluation of Platelet Function:
- Introduction.
- Variables.
- Drawing and Processing Blood for Platelet Aggregation.
- Platelet Aggregation and Secretion.
- Platelet Agonists.
- Clot Retraction.
- Functional Abnormalities of Platelets:
- Introduction.
- Storage Pool Disorders.
- Release Defects.
- Glanzmann's Thrombasthenia.
- Von Willebrand's Disease.
- Bernard Soulier Syndrome.
- Bleeding Time Prolongation.
- Therapeutic Approaches to Inhibition of Platelet Function and Pharmacodynamic Evaluations:
- GPIIb-IIIa Antagonists.
- Other Anti-Platelet Therapies.
- Drugs That May Affect Platelet Function.
- Appendix:
- Recipes for Citrate Based Anticoagulants.
- Inhibitors Used in Platelet Techniques.
- Cytoskeletal Preparation and Recipes.
- Gel-Filtered Platelets.
- Washed Platelets.
- Western Blots of Acrylamide Gels Gell and Blot Recipes.
- Staining of Platelets for Flow Cytometric Analysis.
- Subject Index.
- Basic introduction to platelets
- Laboratory evaluation of platelet function
- Functional abnormalities of platelets
- Therapeutic approaches to inhibition of platelet function.