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Advances in clinical chemistry. Volume 38 /
Volume thirty-eight in the series of the internationally acclaimed Advances in Clinical Chemistry, contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics ranging from basic bio...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; Boston :
Elsevier/Academic Press,
�2004.
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| Colección: | Advances in clinical chemistry ;
v. 38 |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Front Cover; Advances in CLINICAL CHEMISTRY; Copyright Page; CONTENTS; Contributors; Preface; Chapter 1. Lipoprotein Oxidation Products and Arteriosclerosis: Theory and Methods with Applicability to the Clinical Chemistry Laboratory; 1. Introduction; 2. Radicals, Electrophiles, and Other Reactive Species.; 3. Oxidation Products of Lipids and Proteins and Measurement Methods; 4. Detailed Procedures for Some Methods that Measure Oxidation Products in Plasma; 5. Discussion; 6. Conclusion; References
- Chapter 2. Measurement of Matrix Metalloproteinases (MMPs) and Tissue Inhibitors of Metalloproteinases (TIMP) in Blood and Urine: Potential Clinical Applications1. Introduction; 2. Background; 3. Biology and Chemistry of MMPs and TIMPs; 4. Involvement of MMPs and TIMPs in Pathophysiology of Disease; 5. Assays for Measurement of MMPs and TIMPs in Body Fluids; 6. Blood Levels of MMPs and TIMPs in Physiologic and Disease States (Table 2); 7. Miscellaneous Diseases Associated with Increased Levels of MMPs and TIMPs; 8. MMPs Identified in Urine of Patients with Cancer; 9. Conclusions; References
- Chapter 3. Molecular Method to Quantitatively Detect Micrometastases and its Clinical Significance in Gastrointestinal Malignancies1. Introduction; 2. Methodology; 3. Quantitative Detection of Micrometastases and its Prognostic Significance; 4. General Considerations and Future Directions; References; Chapter 4. Zymographic Evaluation of Plasminogen Activators and Plasminogen Activator Inhibitors; 1. Introduction; 2. Monitoring the PA/PAI System; 3. Materials and Methods for Overlay Zymography; 4. Results; 5. Conclusion; References
- Chapter 5. Estrogen Metabolites, Conjugates, and DNA Adducts: Possible Biomarkers for Risk of Breast, Prostate, and Other Human Cancers1. Introduction; 2. Analysis of Estrogens and their Metabolites, Conjugates, and Depurinating DNA Adducts; 3. Biomarkers for Increased Risk of Developing Estrogen-Initiated Cancer; References; Chapter 6. Organophosphates/Nerve Agent Poisoning: Mechanism of Action, Diagnosis, Prophylaxis, and Treatment; 1. Introduction; 2. Chemistry, Mechanism of Action, and Symptoms; 3. Cholinesterase Inhibitors and Other Factors Influencing the Activity; 4. Diagnosis
- 5. Prophylaxis6. Treatment; 7. Future Trends; 8. Summary; References; Chapter 7. The Potential of Protein-Detecting Microarrays for Clinical Diagnostics; 1. Introduction; 2. Diagnostic Signatures; 3. Protein-Detecting Microarrays; 4. Conclusions; References; Chapter 8. Clinical Laboratory Implications of Single Living Cell mRNA Analysis; 1. Introduction; 2. AFM; 3. Manipulations of Biological Material with AFM; 4. mRNA Extraction from Living Cells; 5. Modification of AFM Tips; References; Letter to the Editor; Index; Color Plate Section