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Advances in cancer research. Volume 79 /

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here once again, outstanding and original reviews are presented. Key Features * New Paradigms for the Treatment of Cancer: The Role of Anti-aiogenesis Agents * The Hepatocyte Growth...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Vande Woude, George F., Klein, George, 1925-2016
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press, 2000.
Colección:Advances in cancer research ; v. 79
Temas:
Acceso en línea:Texto completo
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Tabla de Contenidos:
  • Front Cover; Advances in CANCER RESEARCH; Copyright Page; Contents; Contributors to Volume 79; Chapter 1. New Paradigms for the Treatment of Cancer: The Role of Anti-Angiogenesis Agents; I. Introduction; II. Growth Factors and Receptor Tyrosine Kinases; III. Platelet-Derived Endothelial Cell Growth Factor/Thymidine Phosphorylase; IV. Matrix Metalloproteinases; V. Plasminogen Activator/Plasmin System; VI. Integrins; VII. Other; VIII. Conclusions; References; Chapter 2. The Hepatocyte Growth Factor/Met Pathway in Development, Tumorigenesis, and B-Cell Differentiation; I. Introduction
  • II. Structure and Function of HGF and MetIII. HGF/Met in B-Cell Development and Neoplasia; IV. Summary; References; Chapter 3. Clinical Targets for Anti-Metastasis Therapy; I. Introduction; II. Metastasis: Clinical and Experimental Considerations; III. New Tools for Studying the Metastatic Process; IV. New Insights into the Metastatic Process; V. Targets for Anti-Metastasis Therapy: Clinical and Biological Considerations; VI. Conclusions; References; Chapter 4. Animal Models of Melanoma: Recent Advances and Future Prospects; I. Introduction; II. Clinical Aspects of Melanoma
  • III. Molecular Basis for MelanomaIV. Role of Receptor Tyrosine Kinases; V. Model Systems for Melanoma; VI. Conclusions; References; Chapter 5. The Indispensable Role of Microenvironment in the Natural History of Low-Grade B-Cell Neoplasms; I. Introduction; II. More Characters Are Coming on the Stage; III. Conclusions; References; Chapter 6. Epstein-Barr Virus Latency: LMP2, A Regulator or Means for Epstein-Barr Virus Persistence?; I. Introduction; II. EBV Latency; III. Latent Membrane Protein 2; IV. B-Cell Signal Transduction and LMP2A; V. LMP2A Site-Specific Mutant LCLs
  • VI. Model of LMP2A and LMP2B Function in VitroVII. In Vivo Models of LMP2A Function; VIII. LMP2 Function in Epithelial Cells; IX. Discussion; References; Chapter 7. Biochemistry and Pathological Importance of Mucin-Associated Antigens in Gastrointestinal Neoplasia; I. Introduction; II. Biochemistry and Molecular Biology of Mucins; III. Alterations of Mucin Peptide and Mucin Glycosylation during Carcinogenesis; IV. Expression of Mucin-Associated Antigens in Gastric Tissues; V. Expression in Colorectal Tissues; VI. Prognostic Relevance in Gastrointestinal Cancer
  • VII. Serum Tumor Markers (Circulating Antigens)VIII. Functional Aspects Regarding Invasion and Metastasis; IX. Perspectives in Tumor Immunology and Cancer Therapy; References; Chapter 8. Studies on Polyomavirus Persistence and Polyomavirus-Induced Tumor Development in Relation to the Immune System; I. Introduction; II. Initial Studies on Polyomavirus Infection and Polyoma-Specific Immune Reponses in Vivo and in Vitro; III. Molecular Characteristics of Polyomavirus; IV. Polyomavirus Tumor-Specific Transplantation Antigens